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25 Cards in this Set
- Front
- Back
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What are the 2 things that characterize AD?
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abnormally structured neurons and a reduced amount of acetylcholine.
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What are the 2 characteristic features of the AD NEURON?
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1. neurofibrillary tangles extend from the axon to surround the nucleus of the neuron when TAU becomes malformed and misshapen
2.protein-rich accumulations called amyloid plaques evelop branches of the axon. |
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What is the supporting protein of a neuron?
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TAU
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What happens in patience with AD to the supporting protein?
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(TAU) becomes malformed and twists the neurofibrils, which are normally straight causing neurofibrillary tangles.
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what is inside the walls of an axon?
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neurfibrils which are normally straight
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What specific feature of AD would employ neutrophils and macropahges to surround and kill pathogens trying to get a foothold inside the body?
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(inflammatory reaction) The amyloid plaques grow so dense that they trigger the reaction and cause neuron death.
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what is the name of the protein-rich accumulations that envelop branches of the axon on persons with AD?
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amyloid plaques
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What is the treatment for AD?
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Cholinesterase inhibitors
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How do the drugs aricept, cognex, exelon and reminyl work?
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They work at neuron synapses in the brain, slowing the activity of acetylcholinesterase, the enzyme that breaks down acetylchline.
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What would keep memory pathways in the brain functional for a longer period?
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Allowing ACh to accumulate in synapeses by using cholinesterase inhibitors.
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What are the 2 things that characterize AD?
|
abnormally structured neurons and a reduced amount of acetylcholine.
|
|
|
What are the 2 characteristic features of the AD NEURON?
|
neurofibrillary tangles extend from the axon to surround the nucleus of the neuron and protein-rich accumulations called amyloid plaques evelop branches of the axon.
|
|
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What is the supporting protein of a neuron?
|
TAU
|
|
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What happens in patience with AD to the supporting protein?
|
(TAU) becomes malformed and twists the neurofibrils, which are normally straight causing neurofibrillary tangles.
|
|
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what is inside the walls of an axon?
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neurfibrils which are normally straight
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|
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What specific feature of AD would employ neutrophils and macropahges to surround and kill pathogens trying to get a foothold inside the body?
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(inflammatory reaction) The amyloid plaques grow so dense that they trigger the reaction and cause neuron death.
|
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what is the name of the protein-rich accumulations that envelop branches of the axon on persons with AD?
|
amyloid plaques
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What is the treatment for AD?
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Cholinesterase inhibitor OR blocking excitotoxicity: the tendency of diseased neurons to self-destruct.
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How do the drugs aricept, cognex, exelon and reminyl work?
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They work at neuron synapses in the brain, slowing the activity of acetylcholinesterase, the enzyme that breaks down acetylchline.
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What would keep memory pathways in the brain functional for a longer period?
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Allowing ACh to accumulate in synapeses by using cholinesterase inhibitors.
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What do diseased neurons have a tendency to do?
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Self-destruct
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How does memantine (Namenda) contribute to patience with AD?
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it blocks the tendency of diseased neurons to self-destruct.
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When will AD begin in the brain?
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15-20 years before symptoms ever develop.
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What type of lifestyle may prevent AD?
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A lifestyle tailored for good cardiovascular health
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What is the function of Ach?
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Allow Na+ to open which drives neuron closer to threshold.
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