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12 Cards in this Set

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  • Back

Volume of Distribution

Volume in which theamount of drug would need in order for it to be uniformly distributed toproduce the desired blood concentration in mg/ml.i

Onset Of action

The time (hr., min.,etc) at which the administered drug reaches the therapeutic range or it (drug)begins to produce the effect.

Duration of Action

The time span (hr.,min., etc), beginning the onset of action up to the termination of action.

Termination of Action

The time (hr., min.)at which the drug concentration in the plasma falls below the minimum effectiveconcentration (MEC).

Therapeutic Range

The plasmaor serum concentration (mcg/ml, ng/ml etc.) range, within which, the drug islikely to produce the therapeutic activity or effects.

Latent heat of vaporization

heat absorbed (incal/mol or calories/gram) when a liquid vaporizes at normal boiling point.

Saturations Solubility Equilibrium

the maximum amount (mgor g) of a solute that is present in solution form per unit volume of solventat constant temperature or pressure after attainment of equilibrium condition.

Absorption

a process by which theadministered dose of drug travels from the site of administration to the siteof measurement; exists in extravascular route; no absorption for intravascularroute because site of administration and site of measurement are the same.

Heat of Solution

is the heat absorbedor liberated when 1 mole of a solute is dissolved in a definite quantity of apure solvent, say 1000 grams of water, to yield a solution. Cal/mole

Dissolution

The process of powder particles dissolving inthe surrounding fluid to form a solution.

Hygroscopicity

Ability of a powder to adsorbmoisture from the atmosphere

Deliquescence

The amount of moisture adsorb is so high thatthe powder will dissolve and form a solution