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15 Cards in this Set
- Front
- Back
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Narrow tx index drugs
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antiepileptic drugs (phenytoin, carbamazepine), Digoxin, Theophylline
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"red flag" drugs
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cisapride, cyclosporine, MAOi, PIs, warfarin
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CYP450 inh.
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cimetide, ciprofloxacin, e-mycin, itraconazole
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CYP450 inducers
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rifampin, barbiturates, cambamezepine, smoking
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precipitant drugs that affects binding in the gi tract
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calcium, antacids, iron, magnesium, sucralfate
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precipitant drugs that affect binding in the gi tract decreases the absorption of?
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Quinolones, tetracyclines, Methlydopa, levodopa
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solution to interactiing drug with precipitant drugs that affect binding in the gi tract
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administer affected drug 2h before or 6h after precipitant drug -or- administer affected drug through a different route
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precipitant drugs that lowers cholesterol
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cholestyramine and colestipol
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precipitant drugs (binding resins) decreases absorption of ________and solution?
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warfarin and thiazide diuretics (may use colsevalem)
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precipitant drugs that are used for overdoses
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activated charcoal, kaolin-pectin, and antacids
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precipitant drugs used in overdoses decreases the absorption of?
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clindamycin, metronidazole, and digoxin
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precipitant drugs that causes changes in the gastric pH
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antacids, H2RAs, PPIs, didanosine
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precipitant drugs that causes changes in the gastric pH Dec. absorption (therefore dec. F) of ______? and soln.?
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Atazanavir, dapsone, itraconazole, ketoconazole. Administer 2h before or 6h after antacids. for antifungals- may want to switch to fluconazole (do not depend on gastric pH). Monitor the affects of dapsone.
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Precipatant drugs that causes protien binding displacements
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warfarin, tolbutamine, methotrexate, and phenytoin
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Precipatant that causes protien biding displacement displaces?? (therefore inc. their conc.)
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Aspirin, sulfonamides, and chloral hydrate.
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