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5 Cards in this Set

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low iron does what to virulence genes
++ expression
phase variation in salmonella typhimurium
involves rapid reversible switching in synthesis of two alternative flagellar antigens (H1 and H2).
what is the molecular switch that determine which flagellar gene will be transcribed in phase switching
invertible segment of DNA in the promotor of the H2 gene
neisseria gonorrhoea phase variation involves
alternation between antigenic forms of pili on cell surface

each strain of gonococcus has copy of pilin structural gene plus many silent genes.

recombinatorial exchange between the expresed and non-expressed copy of pili genes --> new pilin gene
mechanisms of genetic variation
-spontaneous mutation

-recombination

-acquisition of new DNA segments