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24 Cards in this Set

  • Front
  • Back
The more soluble a drug is in the peripheral tissue...
the greater the volume of distribution
The more __a___a drug is in the __b___ __c___, the _d___the ___e__of __f____
soluble
peripheral tissue
greater
volume of distribution
The central volume of distrubition include all except 1....
heart
bone
liver
lungs
brain
bone
the central volume of distribution include all but...
BONE
Active metabolites of a drug....
INCREASE the duration of effect
what effect to active metabolites of a drug have on the drug?
increas drug's duration
elimination half time is...
time necessary to reduce plasma concentartion to 1/2 inital concentration
an active drug metabolite...
increases the duration of drug effect
do not change the duration
decrease the duration
increase the duration
time necessary to reduce plasma concentartion to 1/2 inital concentration is....
elimination half time
elimination half time is the time necessary to reduce _____to ______
the plasma concentartion
1/2 tjhe initial
a drug is nearly completely eliminated from the body after...
5 half lives
a drug is completely eliminated from the body after___half lives
2
4
5
6
5
examples of benzodiazepines are all but 1....
midazolam
ambien
lorazepam
triazolam
ambien
is ambien a benzodiazepine?
NO
Benzodiazepines act at ____recpetors?
GABA
Benzodiazepines work at ___ receptors
Beta
opioid
gaba
Gaba
examples of antihistamines are all but...
ambient
hydroxyzine
promethazine
ambient
is ambient a antihistamine?
NO
effects of antihistamine are all but...
decrease secretions
decrease pain
cause sedation
decrease nause
decrease pain
do antihistamines decrease pain?
NO
midazolam can be administered in many ways, except...
Oral
Nasal
Rub on skin
Intravenous
rubbing on the skin
can midazolam be administered thru rubbing on the skin?
NO
6. The duration of clinical effect for Valium with an elimination half-life of 40 hours vs Triazolam with an elimination half-life of 1 - 4 hours would be
A. 10 times longer
B. shorter
C. about the same
C
7. What is the most important aspect for successful oral sedation?
A. gender
B. age
C. cooperative
D. weight
C