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24 Cards in this Set
- Front
- Back
The more soluble a drug is in the peripheral tissue...
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the greater the volume of distribution
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The more __a___a drug is in the __b___ __c___, the _d___the ___e__of __f____
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soluble
peripheral tissue greater volume of distribution |
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The central volume of distrubition include all except 1....
heart bone liver lungs brain |
bone
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the central volume of distribution include all but...
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BONE
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Active metabolites of a drug....
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INCREASE the duration of effect
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what effect to active metabolites of a drug have on the drug?
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increas drug's duration
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elimination half time is...
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time necessary to reduce plasma concentartion to 1/2 inital concentration
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an active drug metabolite...
increases the duration of drug effect do not change the duration decrease the duration |
increase the duration
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time necessary to reduce plasma concentartion to 1/2 inital concentration is....
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elimination half time
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elimination half time is the time necessary to reduce _____to ______
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the plasma concentartion
1/2 tjhe initial |
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a drug is nearly completely eliminated from the body after...
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5 half lives
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a drug is completely eliminated from the body after___half lives
2 4 5 6 |
5
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examples of benzodiazepines are all but 1....
midazolam ambien lorazepam triazolam |
ambien
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is ambien a benzodiazepine?
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NO
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Benzodiazepines act at ____recpetors?
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GABA
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Benzodiazepines work at ___ receptors
Beta opioid gaba |
Gaba
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examples of antihistamines are all but...
ambient hydroxyzine promethazine |
ambient
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is ambient a antihistamine?
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NO
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effects of antihistamine are all but...
decrease secretions decrease pain cause sedation decrease nause |
decrease pain
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do antihistamines decrease pain?
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NO
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midazolam can be administered in many ways, except...
Oral Nasal Rub on skin Intravenous |
rubbing on the skin
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can midazolam be administered thru rubbing on the skin?
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NO
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6. The duration of clinical effect for Valium with an elimination half-life of 40 hours vs Triazolam with an elimination half-life of 1 - 4 hours would be
A. 10 times longer B. shorter C. about the same |
C
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7. What is the most important aspect for successful oral sedation?
A. gender B. age C. cooperative D. weight |
C
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