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31 Cards in this Set
- Front
- Back
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Stage I and II Hodgkins
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CT and XRT
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Stage III and IV Hodgkins
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CT
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Diffuse Large B Cell Lymphoma
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CT and Rituximab
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Indolent NHLs
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CT and Rituximab
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Burkitt Lymphoma
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CT
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Cutaneous T Cell Lymphoma
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Early Stage: Treat Topically
Advanced Stage: Immunoconjugate of IL2 and Diptheria toxin |
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Multiple Myeloma
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Thalidomide, Lenalidomide (IMIDs)
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Multiple Myeloma Supportive Care for Bone Destruction
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Biphosphonates stop bone turnover (Good except in dental work)
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Waldenstrom's Macroglobulinemia
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Plasmapheresis
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CLL
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Bendamustine (Purine analogue with characteristic of alkylating agent)
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ALL
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CT and l-asparaginase
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AML- Ab treatment
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Gemtuzumab (This cell expresses CD33)
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AML- Induction Therapy
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CT: Anthracycline + Cytarabine to achieve aplasia
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APL (M3 AML) : Consumptive Coagulopathy
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FFP, Platelets, Fibrinogen and Platelets
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APL (M3 AML):
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ATRA or Arsenic- induces release of nuclear corepressor complex
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Myelodysplasia
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Lenalidomide in patients with the 5q deletion
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Thrombocythemia
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Hydroxyurea
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Polycythemia Vera
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Phlebotomy
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CML
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Imatinib
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Iron Deficiency
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Ferrous Sulfate Salts on empty stomach
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Anemia of Chronic Disease
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Generally mild so no treatment
EPO if necessary |
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Sideroblastic Anemia
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Transfusions and Desferrioxamine (To prevent Fe Toxicity)
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Thalassemias
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No treatment necessary except for B Thal Major (Transfuse)
Do genetic counseling |
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B12 Deficiency
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IM B12 1mg/mos
Oral B12 1mg/day |
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Folate Deficiency
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400 micrograms until confirmed
Oral 1 mg/day |
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Hereditary Spheroytosis
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Splenectomy
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G6PD Deficiency
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Hemolysis is Self Limited despite continued use of causative drugs (or beans or infection) but in severe cases the offending drug can be removed
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Sickle Cell Anemia
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Prophylaxis against capsulated bacteria in children
Analgesics and Hydration during crises Transfusions only for ACS and stroke prevention Hydroxyurea to increase HbF |
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Warm AIHA
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Prednisione
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Cold Agglutinin Disease
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Avoid Cold
Prednisone not effective like for Warm AIHA Treat underlying disease (EBV, Mycoplasma) |
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Paroxysmal Nocturnal Hemoglobinuria
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Alternate Day Corticosteroids
Eculizumab (Ab against C5) |
