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36 Cards in this Set

  • Front
  • Back
Microtubules are composed of?
Alpha and Beta
Minus End?
Alpha
Beta End?
Plus
Which end grows fast?
Beta
How are microfilaments bonded?
noncovalent interaction
What is bound to Beta Tubulin?
GTP
What happens when GTP is bound to alpha?
Nothing, doesn't get hydrolyzed
What happens when GTP cap is lost?
The microtubules SHRINK!
What is stochastic?
Happens randomly, GTP hydrolysis happens randomly
What does Taxol do specifically to the microtubules?
binds and stablize microtubules
What types of organization occurs in microtubules?
Radial, spindle, cilia and flagella
What are the roles of the centrosome?
To build
Do microtubules always need centrosomes to organize themselves?
No, plants do not need it, they also use gamma ring complex
How many doublets and central microtubles
9 doublets and 2 central mt
What types of intracellular movements are they responisble for?
Long distance movement of organelles and spindle formation in mitosis
What are the motor proteins associated with microtubules?
Dyneins and kinesins
What movement does dyneins favor?
Towards minus end, alpha
What movement does kinesin favor?
plus end,
What gives the microtubules directionality
Head
What holds or binds the cargo?
Tail
What is the lagging head of motor proteins composed of?
ATP
What is the leading head of motor proteins composed of?
ADP
What are actin filaments composed of?
2 helical strands of globulin actin monomers
What are the ends?
Barbed and pointed end
What is the barbed end?
The plus end, grows fast
What is the pointed end?
The minus end, grows slowly
Filipodium
bundle of 5-20 filaments
Lamellopodium
meshwork
stress fibers
bundle
What comples aids the formation of action?
ARP 2/3
What are the actin motor proteins?
myosin
What type of myosin moves to the minus pointed end?
Myosin 6
Which myosin is a muscle and non muscle?
Conventional myosin II
name an unconventional motor protein of actin
myosin V
Why is myosin 5 unconventional
its head has a high affinity for actin, it can hold on by one arm, it also has a long neck and can use it to swing
Septin
associated with MC and Actin