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36 Cards in this Set
- Front
- Back
Microtubules are composed of?
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Alpha and Beta
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Minus End?
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Alpha
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Beta End?
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Plus
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Which end grows fast?
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Beta
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How are microfilaments bonded?
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noncovalent interaction
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What is bound to Beta Tubulin?
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GTP
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What happens when GTP is bound to alpha?
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Nothing, doesn't get hydrolyzed
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What happens when GTP cap is lost?
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The microtubules SHRINK!
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What is stochastic?
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Happens randomly, GTP hydrolysis happens randomly
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What does Taxol do specifically to the microtubules?
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binds and stablize microtubules
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What types of organization occurs in microtubules?
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Radial, spindle, cilia and flagella
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What are the roles of the centrosome?
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To build
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Do microtubules always need centrosomes to organize themselves?
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No, plants do not need it, they also use gamma ring complex
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How many doublets and central microtubles
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9 doublets and 2 central mt
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What types of intracellular movements are they responisble for?
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Long distance movement of organelles and spindle formation in mitosis
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What are the motor proteins associated with microtubules?
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Dyneins and kinesins
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What movement does dyneins favor?
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Towards minus end, alpha
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What movement does kinesin favor?
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plus end,
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What gives the microtubules directionality
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Head
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What holds or binds the cargo?
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Tail
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What is the lagging head of motor proteins composed of?
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ATP
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What is the leading head of motor proteins composed of?
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ADP
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What are actin filaments composed of?
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2 helical strands of globulin actin monomers
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What are the ends?
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Barbed and pointed end
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What is the barbed end?
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The plus end, grows fast
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What is the pointed end?
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The minus end, grows slowly
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Filipodium
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bundle of 5-20 filaments
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Lamellopodium
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meshwork
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stress fibers
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bundle
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What comples aids the formation of action?
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ARP 2/3
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What are the actin motor proteins?
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myosin
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What type of myosin moves to the minus pointed end?
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Myosin 6
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Which myosin is a muscle and non muscle?
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Conventional myosin II
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name an unconventional motor protein of actin
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myosin V
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Why is myosin 5 unconventional
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its head has a high affinity for actin, it can hold on by one arm, it also has a long neck and can use it to swing
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Septin
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associated with MC and Actin
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