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12 Cards in this Set

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proteins and phospholipids synthesized where
Rough ER are transported to the Golgi complex and then to secretory vesicles destined to fuse with the cell membrane via exocytosis
endosomes
membrane taken into the cell in fthe form of endocytic vesicles is incorporated into early endosomes which are sorting compartments concentrated at the cell's periphery
nuclear envelope
portion of rough ER which surounds chromosomal DNA; interrupted by nuclear pores which are hydrophilic channels through which proteins and RNA are exchanged between the cytoplasm and the nuclear cytoplasm
mitochondria
generate ATP
peroxisomes
engage in detoxification through peroxidation reactions and prevent the accumulation of the strong oxidizing agent hydrogen peroxide
smooth ER
functions as a regulated calcium store and also involved in lipid metabolism
microtubules
largest diamter fibers 25 nm; extend the full length of the neuron and form long scaffolds
are constrcted of 13 protofilaments in a tubular array each protofilament consists of several pairs of alpha and beta tubulin subunits `
tubulin
is a GTPase
how do microtubules grow
by the addition of GTP-bound tubulin dimers at their plus end
MAPs
microtubule associated proteins; MAP2 is present in dendrites but not axons
promote the oriented polymerization and assembly of the microtubules
neurofilaments
10nm in diameter are the most abundant fibrillar components of the axon; they are very stable and amost totally polymerized
chaperones
proteins that bind to unstructured exposed regions of the newly synthesized polypeptide