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24 Cards in this Set
- Front
- Back
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IL-1
Secreted by: Fcn: Anything special? |
Secreted by Macrophages
Acute phase reactant, activates endothelium to express adhesion molecules Endogenous pyrogen |
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IL-2
Secreted by: Fcn: |
Secreted by Th1 cells
Stimulates growth of CTLs and Th cells |
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IL-3
Secreted by: Fcn: |
Secreted by activated T cells
Supports growth and differentiation of BM stem cells |
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IL-4
Secreted by: Fcn: |
Secreted by Th2 cells
Promotes growth of B cells Causes class switching to IgE & IgG |
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IL-5
Secreted by: Fcn |
Secreted by Th2 cells
Promotes differentiation of B cells, enhances class switching to IgA, & stimulates production & activation of eosinophils |
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IL-6
Secreted by: Fcn: |
Secreted by Th cells & Macrophages; stimulates production of acute phase reactants & immunoglobulins
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IL-8
Secreted by: Fcn: |
Secreted by Macrophages. Major chemotactic factor for PMNs
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IL-10
Secreted by: Fcn: |
Secreted by regulatory Th2. Activates Th2, inhibits Th1 & Macrophages
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IL-12
Secreted by: Fcn: |
Secreted by B cells & Macrophages. Activates NK & Th1 cells
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ϓ-interferon
Secreted by: Fcn: |
Secreted by Th1 cells.
Stimulates macrophages, activates Th1, inhibits Th2 |
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TNF
Secreted by: Fcn: |
Secreted by macrophages
mediates septic shock recruits WBCs & causes vascular leakage |
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What cell has this cell surface marker?
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Pick the cell that matches the cell surface protein
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CD3
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Th cells, CTLs
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CD19
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B cells
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CD 40
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B cells, Macrophages
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CD16
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NK cells & Macrophages
(First Aid says NK cells, but DIT says also on MOs) |
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Function of CD16
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Binds Fc of IgG
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CD56
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NK cells
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CD55 & CD59
What is their function? |
WBCs, RBCs, platelets
Prevents complement mediated damage AKA: Decay Accelerating Factor (DAF) Deficiency leads to Paroxysmal Nocturnal Hemoglobinuria (PNH) |
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What cell has receptors for Fc and C3b?
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Macrophages
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CD28
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Th cells
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CD40L
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Th cells
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What is the receptor for EBV, and what cell has it?
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CD21, B cells
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B7
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B cells and Macrophages
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