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11 Cards in this Set
- Front
- Back
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IL-1
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secreted by macrophages
causes acute inflammation induces chemokine production to recruit leukocytes; activates endothelium to express adhesion molecules endogenous pyrogen |
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IL-2
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secreted by Th cells
stimulates groeth of helper and cytotoxic T-cells |
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IL-3
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Secreted by activated T-cells
supports growth and differentiation of bone marrow stem cells. Has a function similar to GM-CSF |
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IL-4
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Secreted by Th2 cells
Promotes Growth of B-cells Enhances class switching to IgE and IgG |
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IL-5
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Secreted by Th2 cells
Promotes differentiation of B-cells enhances class switching to IgA Stimulates production and activation of eosinophils |
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IL-6
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Secreted by Th cells and macrophages
stimulates production of acute phase reactants and immunoglobulins |
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IL-8
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secreted by macrophages
major chemotactic factor for neutrophils |
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IL-10
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Secreted by regulatory T-cells
Inhibits actions of activated T-cells |
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IL-12
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secreted by B cells and macrophages
activates NK and Th1 cells |
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Ƴ-inteferon
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secreted by Th1 cells
secreted by macrophages |
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TNF
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secreted by macrophages
mediates septic shock causes leukocyte recruitment vascular leak |
