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14 Cards in this Set
- Front
- Back
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Interleukin-1
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Secreted by everything under the sun to induce inflammation, fever, acute phase response.
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Interleukin-2
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Secreted by active T-cells to stimulate differentiation of T & B Cells, activates NK cells
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Interleukin-3
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Secreted by T cells and granulocytes. Induces colony formation of non-lymphatic immune cells.
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Interleukin-4
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Secreted by TH2 cells to induce TH2 differentiation. Promotes proliferation of B-cells, class switching to IgE and allergen response.
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Interleukin-5
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Secreted by T-cells. Induces Eosinophil proliferation, B-cell proliferation.
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Interleukin-6
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Secreted by some B and T cells, induces hematopoeisis, Inflammation.
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Interleukin-7
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Secreted in bone marrow and thymus by stromal cells. Growth factor for Lymphocyte progenitors.
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Interleukin-8
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Chemoattractant for Neutrophils and company.
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Interleukin-9
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Secreted by some helper T-cells. Stimulates proliferation of T-lymphocytes.
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Interleukin-10
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Secreted by T-cells, Macrophages, Dendritic Cells. Anti-inflammatory, stimulates IgA synthesis.
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Interleukin-12
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Secreted by Macrophages, B-cells, Dendritic cells. Important in differentiation to TH1 cells. Increases cytotoxic response.
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Interleukin-14
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Secreted by active T-cells. Enhances B-Cell proliferation but decreases antibody synthesis.
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Interleukin-16
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Secreted by dendritic cells. Chemoattractant for CD4+ cells. (NOTE: inhibits HIV binding.)
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Interleukin-17
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Secreted by TH17 cells among others. Induces the inflammatory response.
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