Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
IL-1
|
from macrophages
causes fever and inflammation endothelial adhesion molecule expression chemokine secretion for leukocytes |
|
|
IL-2
|
from Th1 cells
stimlates Th/Tc growth |
|
|
IL-3
|
from all T cells
supports bone marrow stem cells like GM-CSF |
|
|
IL-4
|
from Th2 cells
promotes IgE/IgG class switching promotes Th2 differentiation |
|
|
IL-5
|
from Th2 cells
promotes IgA class switching stimulates eosinophils |
|
|
IL-6
|
from macrophages and Th
causes fever and acute-phase protein production |
|
|
IL-8
|
from macrophages
neutrophic chemotactic factor |
|
|
IL-10
|
from Th2 and regulatory T cells
modulates inflammation (similar to TGF-beta) inhibits T cells and Th1 activates Th2 |
|
|
IL-12
|
from macrophages and B cells
induces Th1 differentiation activates NK cells |
|
|
Interferon-gamma
|
from Th1 cells
activates macrophages and Th1 supresses Th2 cells antiviral/antitumor |
|
|
TNF-alpha
|
from macrophages
causes septic shock endothelial activation, leukocyte recruitment, and vascular leakage |
