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22 Cards in this Set
- Front
- Back
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This reoccurant inflammatory disease occurs 1-6 week post Group A Strep infection and occurs mainly in children ages 5-15 years
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Acute Rheumatic Fever
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Patho genesis of ARF (Acute Rheumatic Fever)
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host anti strep antibodies are cross reactive to cardiac antigens
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Major Jones Criteria for ARF
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Erythema Marginatum
Sydeham chorea Carditis Subcutaneous nodules Migratory large joint polyarthritis |
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Minor Jones critieria for ARF
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Fever
Arthralgia LAB: elevated acute phase reactants, c reactive protein, alpha 1 antitrypsin Prolonged PR interval |
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In ARF, death is rare and is usually secondary to ___________
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myocarditis
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Chronic rheumatic heart disease may eventually lead to _____
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CHF
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What some of the main physical changes associated with Rhematic Heart Disease?
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Mitral valve damage--- Mitral Stenosis
Left atrial/ Right Ventricular hypertrophy |
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What are the Gross finding of Rheumatic Heart DIsese?
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acute valvulitis with formation of beady fibrinous vegetations
calcification accurs deep within the leaflets and shortened and thinning chordae and pappilary muscles |
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What are 2 of the pathonomonic micro finding of rhematic heart disease?
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Aschoff bodies/ nodules--- granulomatous inflammation with giant cell infiltrate
Anitschkow cell --- long this cell with an elongated nucleus |
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In chronic rheumatic disese the mitral valve will present in a _______ appearance on autopsy.
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"fish mouth" calcific
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What is the main diagnostic lab test used to evaluate rheumatic heart disease?
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Anti Streptolysin O titers
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How much fluid is typically present in the pericardium?
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20 cc
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Describe serous acute pericarditis.
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the slow accumulation of 50-200 cc of non-bacterial pericardial fluid
Idiopathic |
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What is the most common pericardial disease? Describe
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Fibrinous and Serofibrinous
seen with an MI and produces a friction rub on auscultation May resolve without sequelae |
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What is the most common causitive agent of purulent pericardial disease?
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Gram positive staph, strep and pneumococci
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What would happen if pericardial fluid were to accumulate too fast?
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Cardiac tamonade
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What are the two types of acute pericarditis?
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Hemmorhagic and Caseous
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Hemorrhagic acute pericarditis.....
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most oftern occurs after cardiac surgery or associated with TB or malignancy
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Caseous Acute pericarditis....
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is secodary to TB
usually a direct extension from lymph nodes (fibrocalcific constrictive pericarditis) |
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What is hemopericardium?
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Blood in the pericardial sac without inflammation
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Chronic pericarditis is usually secondary to what diseases?
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TB
Purulent pericardidtis |
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The thick, dense, fibrous obliteration of the pericardial sac that happens with TB associated chronic pericarditis usually limits ________ and restricts _________
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diastolic expansion
cardiac out put |
