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33 Cards in this Set

  • Front
  • Back
What is the definition of severe HTN?
diastolic of 115 or higher
What is the definition of hypertensive emergency?
acute elevation of BP causes rapid and progressive end organ damage
What % of patients with HTN have end organ damage?
<1%
What % of medical urgency/emergency is due to hypertensive crisis?
25%
What are some signs of urgency? Emergency?
1. H/A, epistaxis, faintness
2. chest pain, dyspnea, neuro deficit
What are some end organ damages?
1. cerebral infarct
2. acute pulmonary edema
3. hypertensive encephalopathy
4. cerebral hemorrhage
What is the goal of hypertensive emergency treatment?
1. lower mean arterial pressure by 20-25% or reduce diastolic pressure to 100-110 over 24-48 hours
What happens if blood pressure is dropped too quickly?
ischemia
What should urine output be maintained at in hypertensive emergency?
>20m/hr
What drugs are used to treat hypertensive encephalopathy?
1. nitroprusside-instantaneous
2. labetalol-give IV bolus, then TKO
3. fenoldopam-vomiting
4. nitroglycerin-MI's
What 3 drugs are given during an MI?
1. nitroglycerine infusion
2. morphine
3. beta blocker
What effect does nitroglycerine have on MI?
decreases preload, afterload, and dilates coronary arteries
How can morphine affect an MI patient?
decreses pain, which drops BP, which decreases preload and vasodilates patient
What drugs are used to treat CHF?
1. nitroglycerine
2. morphine
3. nitroprusside
4. fenoldopam
What drugs are used to treat renal failure?
1. nitroprusside
2. labetalol
3. fenoldopam
What drugs are used to treat an aortic dissection?
nitroprusside and beta blocker
What drug is used in black males to treat CHR and HTN?
hydralazine
What are some sx of hypertensive emergencies?
1. HTN
2. H/A
3. N & V
4. seizures
5. retinopathy
6. visual disturbances
7. thrombosis
8. acute renal failure
9. chest pain
10. dyspnea/orthopnea
11. focal neuro deficits
12. stupor coma
13. pulmonary edema
14. hemorrhage
15. embolus
16. abnormal pain
What meds can cause hyptertensive emergencies?
1. decongestants
2. steroids
3. drugs of abuse
4. amphetamines
5. appetite suppression
6. MAO inhibitors
7. cocaine
What are some events that can cause hypertensive emergency?
1. withdrawal of antihypertensive
2. withdrawal of CNS depressant
3. eclampsia
4. TTP
5. pheochromocytoma
6. idiopathic hyptertensive
7. renal disease
8. severe burns
9. post operative hypertensive
10. aneurysm
What would be a clue to a coarctation?
normal BP in one arm, very high in the other
What might show up on a CBC that would be a clue to hypertensive crisis?
1. hemolytic anemia
2. thrombocytopenia
3. microantiopathies
What might the serum electrolytes show in a hypertensive emergency?
hypokalemic acidosis
What is the formula for mean arterial pressure?
diastolic + (systolic-diastolic)
Can nitroprusside be given during pregnancy?
no
How long does labetalol take to have effect?
10-15 minutes
Should diaoxizide be used in hypertensive emergency?
no, bottoms out BP too quickly
What kind of drug is trimethaphan? Who uses it?
1. ganglionic blocker
2. neurosurgeons
What kind of drug is magnesium sulfate? Who is this usually used for?
1. vasodilator
2. pregnant women
What can happen in magnesium sulfate overdose?
paralysis
What other drugs can phentolamine be used with?
only with lanoxin and insulin
What vasodilator is recommended in pregnancy?
hydralazine
Furosemide is used with what other drug to treat hypertensive pulmonary edema?
nitroglycerine