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34 Cards in this Set

  • Front
  • Back
Which bacteria is the most common cause of skin infections?
S. aureus
What skin infections can be caused by S. aureus?
Impetigo
Furuncles (boils)
Carbuncles
Superficial and deep folliculitis
Cellulitis
Paronychia
What skin infections are caused by GAS?
Impetigo
Blistering distal dactylitis
Ecthyma
Erysipelas
Cellulitis
Necrotizing fasciitis
What are the differences between impetigo contagiosum and bullous impetigo? (3)
Contagiosum can be caused by S. aureus and GAS, bullous is only by S. aureus
Contagiosum has surrounding erythema and bullous does not
Bullous has exotoxin involvment, contagiosum does not
What is staphylcoccal scalded skin syndrome?
Pharyngeal, nasal or conjunctival infection that produces exfoliative exotoxins types A and B which spread systemically causing exfoliation of skin
What are furuncles and carbuncles and what bacteria are they caused by?
A furuncle is a deep follicular abcess (boil) that can progress to a carbuncle which is a group of adjoining furuncles that is more likely to develop complications. S. aureus is cause.
What is paronychia?
Infection of nailfolds with strep or staph leads them to become purulent, swollen and tender
What is blistering distal dactylitis?
Tender superficial bulla on an erythematous base on volar fat pad of fingers.
Caused by GAS
Found in young children
What is Ecthyma?
A severe form of Streptococcal impetigo where there is a thick crust over a punched out ulcer usually found on the lower legs
What is erysipelas
poinful acute infection of the skin involving the superficial dermal lymphatics.
Associated with fever and malaise
Main cause is GAS
What bacteria causes necrotizing fasciitis type II?
GAS
What lab tests can be used for diagnosis of HSV I, HSV II and VZV, and which ones are able to differentiate these different viruses? (4)
1. Tzanck smear - cannot differentiate
2. Direct fluorescent antibody test - can differentiate HSV1/2 and VZV and results available in hours
3. Viral culture - can differentiate HSV1/2 and available in 2-3 days
4. PCR - do not need active lesion - can differentiate HSV 1/2 and VZV
What are abnormal presentations of HSV 1? (3)
Herpes gladiatorum - wrestler/rugby players
Herpetic Whitlow - fingers
Herpetic Keratoconjunctivities - can lead to blindness
Are HSV 1 and HSV 2 primary infections symptomatic or asymptomatic?
HSV 1 - usually asymptomatic
HSV 2 - 80% symptomatic
What are severe manifestations of HSV infection? (3)
Neonatal HSV (HSV2>HSV1)
HSV encephalitis (HSV1>HSV2)
Eczema herpeticum - HSV in eczema which spreads systemically and can be fatal
What can be used to prevent HSV-1 recurrence?
Sunscreen
Valcyclovir at onset of prodrome
Famciclovir or valcyclovir for prophylaxis
How do you treat HSV-2 infection? (2 strategies)
Intermittant therapy (for few or mild recurrences) - initiate acyclovir, famcyclovir or valcyclovir at earliest sign of recurrence
Suppressive therapy (for frequent/severe recurrences or non-infected partner) - acyclovir BID, famcyclovir BID or valcyclovir OD
How do you treat VZV infection?
Do nothing in healthy children
Acyclovir in older or unhealthy children
When can maternal infection with VZV occur?
First 20 weeks of pregnancy
What is Hutchinson's syndrome?
Zoster on tip of nose indicating VZV infection of V1 division of CN V (ocular)
How do you treat zoster?
7 days of valcyclovir or famcyclovir
What is molluscum contagiosum caused by?
Poxvirus
What 3 populations are susceptible to getting molluscum contagiosum?
Young children
Sexually active adults
Immunosuppressed
What are 4 types of warts and the locations they typically appear?
Verruca vulgaris (common wart) - hands
Verruca plana (flat warts) - face, neck and dorsum of hands
Plantar warts - bottoms of feet
Genital warts - genitals
How do you treat non-genital warts? (8)
No treatment
Cryotherapy
Topical salicylic acid
Trichloroacetic acid
Topical tretinoin
Pulsed dye laser
CO2 laser
Electrodessication
Which are the high risk genital wart HPV strains?
16, 18 (6, 11)
How do you treat genital warts?
Cryotherapy (safe in pregnancy)
Imiquimod
Trichloroacetic acid (safe in pregnancy)
CO2 laser (safe in pregnancy)
5 fluorouracil
What is the most common dermatophytoses?
Tinea pedis
What is the most common cause of tinea pedis?
Trichophyton rubrum
What tissues can dermatophytes infect?
Only keratinized tissue (Stratum corneum,hair and nails)
How do you treat dermatophytoses?
Terbinafine cream
Oral terbinafine
What are common variants of dermatophytoses?
tinea pedis, capitis, corporis, curis, onychomycosis
What is the most common cause of yeast infection?
Candida albicans (70-80%)
What are common types of skin infections caused by fungi?
Tinea, onychomycosis, candidiasis, pityriasis versicolor