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47 Cards in this Set
- Front
- Back
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What 2 components make up the ECM?
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1. Ground substance
2. Fibers |
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Characteristics of ground substance?
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Hydrated & amophorous
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Ground susbtance is composed of?
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Glycosaminoglycans (GAGs)
Proteoglycans Adhesive glycoproteins |
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What types of fibers make up ECM?
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1. Collagen
2. Elastic 3. Reticular |
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What is the most widespread form of collagen in CT proper, bone, dentin & cementum?
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TYPE I collagen
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Which type of collagen is found in cartilage?
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Type II collagen
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Which type of collagen is found in reticular fibers?
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Type III collagen
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WHich type of collagen is found in basal lamina?
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Type IV collagen
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Elastic fibers are composed of?
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Elastin & microfibrils
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What are the most abundant CT cell?
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Fibroblasts
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What are fibroblasts derived from?
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Mesenchymal cells
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What types of cells are considered to be an intermediate between fibroblasts & smooth muscle cells?
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Myofibroblasts
-Bundles of actin & myosin -Similar shape to fibroblasts |
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Myofibroblasts are found where?
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Wound healing & PDL
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What are pericytes?
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Intermediate between endothelial cells & smooth muscle cells
-Partially surround endothelial cells of capillaries & small venules |
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What is significant about pericytes?
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Multipotential-- can differentiate into other cell types
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What are the function of adipocytes?
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Synthesize & store triglycerides
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What are the 2 types of adipocytes?
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1. Unilocular adipocytes
2. Multilocular adipocytes |
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Which adipocyte has many small lipid droplets in cytoplasm & also large numbers of mitochondria?
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Multilocular adipocytes
"Brown fat" -Involved in heat generation |
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Which type of adipocyte is one single large lipid droplet filling entire cell?
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Unilocular adipocyte
"White fat" |
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The cytoplasm of mast cells is filled w/ basophilic granules containing?
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heprarin, histamine, proteases...
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What activates mast cells?
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Binding IgE to Fc receptors in response to foreign antigens
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Macrophages arise from?
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Monocytes
-Members of the mononuclear phagocyte system |
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Macrophages in the liver are known as?
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Kupffer cells
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Macrophages in the lungs are known as?
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Dust cells or Alveolar macrophages
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Macrophages in the skin are known as?
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Langerhans cells
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Macrophages in bone are known as?
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Osteoclasts
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Macrophages in brain are known as?
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Microglial
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Which cell has "clock face" nucleus?
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Plasma cells
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Activated B lymphocytes are?
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Plasma cells
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What is function of plasma cells?
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Produce Ab
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What cell types are found in CT?
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1. Fibroblasts
2. Myofibroblasts 3. Pericytes 4. Adipocytes 6. Mast cells 7. Macrophages 8. Plasma cells 9. Leukocytes |
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What types of connective tissues are there?
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1. Mesenchymal CT
2.Mucous CT 3. Loose (areolar) CT 4. Dense CT 5. Reticular CT 6. Adipose 7. Specialized |
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What types of CT are embryonic?
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Mesenchymal CT & Mucous CT
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Mesenchymal CT contains?
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Mesenchymal cells (pluripotent stem cells)
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Mesenchymal cells are though only to persist where in adults?
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Pulp
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Undifferentiated mesenchymal cells have potential to differentiate into?
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1. Fibroblast
2. Adipocyte 3. Chondroblast --> chondrocytes 4. Osteoblasts --> osteocyte 5. Odontoblasts 6. Cementoblasts |
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What is mucous CT?
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Loose amorphous tissue found only in umbilical cord
"Wharton's Jelly" |
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Which type of CT has abundant ground substance & tissue fluid?
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Loose Areolar CT
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Which type of CT is found in:
-dermis -mesothelium -adventitia of vessels -stroma of glands - lamina propria of digestive & respiratory? |
Loose (areolar) CT
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Which type of CT has collagen fibers in multiple orientations which resists stress in all directions?
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Dense irregular CT
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Which type of CT is found in:
-Dermis -Nerve sheaths -Spleen capsule -Testes -Ovaries -Kidneys -Lymph nodes |
Dense irregular CT
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Which type of CT has collagen bundles packed parallel to each other which resist tensile forces?
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Dense regular collagenous CT
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What type of CT is found in:
-Tendons -Ligaments -Aponeurosis |
Dense regular collagenous CT
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Which type of CT contains mostly elastic fibers w/ little collagen?
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Dense regular elastic CT
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Which type of CT is found in:
-Blood vessels -Ligamentum flavum (vertebral colum) -Suspensory ligament of penis |
Dense regular elastic CT
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Which type of CT contains type III collagen meshwork which supports parenchyma?
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Reticular CT
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What type of CT is found in:
-Liver sinuosoids -Adipose tissue -Bone marrow -Lymph nodes & spleen -Smooth muscle -Islets of Langerhans |
Reticular CT
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