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81 Cards in this Set

  • Front
  • Back
Bioenergetics
Flow of energy in a Biological system

Concern Primarily the conversion of MacroNutrients
- CHO
- PRO
- FAT
Energy
Ability/Capacity to perform work
Catabolism
The breakdown of Large molecules into Smaller molecules

Associated with the Release of Energy
Anabolism
The Synthesis of Larger molecules from Smaller molecules from E+
Exergonic Reaction
Energy Releasing Reactions

Generally Catabolic
Endergonic Reaction
Require Energy

Include Anabolic Processes

Contraction of Muscles
Metabolism
The total of all the Catabolic (Exergonic) and Anabolic (Endergonic) Reactions in a biological system
Adenosine Triphosphate (ATP)
ATP allows the transfer of Energy from Exergon to Endergon Reactions
Hydrolysis
The breakdown of one Molecule of ATP to yield energy

B/C it requires one Molecule of H2O
Adenosine Triphosphatase (ATPase)
The enzyme that catalyzes ATP hydrolysis
Myosin ATPase
Specifically, the enzyme that catalyzes ATP hydrolysis for Cross-Bridge Recycling
Calcium ATPase
Enzyme for ATP Hydro

For Pumping Ca back into the SR
Sodium-Potassium ATPase
Enzyme for ATP Hydro

For Maintaining the Sarcolemmal concentration gradient Post-Depol
Adenosine Diphosphate (ADP)
Byproduct of Hydro of ATP

Only two Phosphate Groups
Adenosine Monophosphate (AMP)
Byproduct of Hydro of ADP
Anaerobic
Processes that do not require the presence of O2
Aerobic
Mechanisms that depend on O2
3 Systems of ATP Replenishment
Phosphagen

Glycolytic

Oxidative
Phosphagen System
Provides ATP primarily for:
- Short-Term
- High Intensity
Activities

Also, it's the reactive Start of ALL exercise regardless of intensity
Creatine Phosphate (CP) / Phosphocreatine (PCr)
High energy phosphate molecules used for E+ reproduction in the Phosphagen system
Creatine Kinase
The enzyme that catalyzes the synthesis of ATP from CP and ADP
Adenylate Kinase (aka Myokinase) Reaction
An important Single-Enzyme reaction that can rapidly replenish ATP
Type II Muscles and CP
Type II muscles have higher concentrations of CP
Law of Mass Action (aka Mass Action Effect)
Phosphagen system control

States:
- Concentrations of Reactants/Products (or both), in a solution, will Drive the Direction of the Reactions.
Near-Equilibrium Reactions
Slow Steady, equal Reaction

Proceed in a direction dictated by the concentrations of the Reactants due to the Law of Mass Action
Glycolysis
The breakdown of CHO

Either Glycogen stored in muscles
or
Glucose delivered in the Blood

To Resynthesize ATP
Pyruvate
The end result of Glycolysis

Can be converted to Lactate or Shuttled to Mitochondria
Anaerobic Glycolysis (Fast Glycolysis)
When Pyruvate is converted to lactate
- ATP Resynthesis occurs at a faster rate
- Limited duration
Aerobic Glycolysis (Slow Glycolysis)
When Pyruvate is shuttled into the Mitochondria for Krebs Cycle
- ATP Resynthesis rate is slower
- Occurs for Longer Duration during low intensity exercise
Lactate
Pyruvate is converted into lactate to be mobilized throughout the body
Creatine Kinase
The enzyme that catalyzes the synthesis of ATP from CP and ADP
Adenylate Kinase (aka Myokinase) Reaction
An important Single-Enzyme reaction that can rapidly replenish ATP
Type II Muscles and CP
Type II muscles have higher concentrations of CP
Law of Mass Action (aka Mass Action Effect)
Phosphagen system control

States:
- Concentrations of Reactants/Products (or both), in a solution, will Drive the Direction of the Reactions.
Near-Equilibrium Reactions
Slow Steady, equal Reaction

Proceed in a direction dictated by the concentrations of the Reactants due to the Law of Mass Action
Glycolysis
The breakdown of CHO

Either Glycogen stored in muscles
or
Glucose delivered in the Blood

To Resynthesize ATP
Pyruvate
The end result of Glycolysis

Can be converted to Lactate or Shuttled to Mitochondria
Anaerobic Glycolysis (Fast Glycolysis)
When Pyruvate is converted to lactate
- ATP Resynthesis occurs at a faster rate
- Limited duration
Aerobic Glycolysis (Slow Glycolysis)
When Pyruvate is shuttled into the Mitochondria for Krebs Cycle
- ATP Resynthesis rate is slower
- Occurs for Longer Duration during low intensity exercise
Lactate
Pyruvate is converted into lactate to be mobilized throughout the body
Metabolic Acidosis
The process of an Exercise-Induced Decrease in pH

Inhibits the enzymatic turnover rate of cell's E+ systems
Wet Muscle
Muscle that has not been Desiccated
Cori Cycle
Process of transporting Lactate in the blood to the liver
>
Then converted to Glucose
Mitochondria
Specialized cellular organelles where the reactions of aerobic metabolism occur
Reduced
Refers to the addition of Hydrogen
Phosphorylation
The process of adding an inorganic Phosphate (Pi) to another Molecule
Oxidative Phosphorylation
The resynthesis of ATP in the Electron Transport Chain
Substrate-Level Phosphorylation
The direct resynthesis of ATP from ADP during a single reaction in the Metabolic Pathways
Allosteric Inhibition
When an end Product Binds to the Regulation Enzyme
- Decreases turnover rate
- Slows production formation
Allosteric Activation
When an "Activator" binds with the enzyme and
- Increases its turnover rate
Rate-Limiting Step
The slowest step of a chemical reaction
- Limits and controls rate of reaction
Lactate Threshold (LT)
Intensity at which Blood Lactate
- Begins an Abrupt increase above baseline
- Marker of Anaerobic Threshold
Onset of Blood Lactate Accumulation (OBLA)
When the concentration of Blood Lactate reaches:
- 4 mmol/L
- During very Intense exercise
- Second increase of Lactate accumulation after LT
Oxidative System
The primary source of ATP at:
- Rest
- Low Intensity Exercise

Uses Primarily:
- CHO
- FAT
Krebs Cycle
A series of reactions that
- Continues to Oxidate the substrate from Glycolysis
- Produces two ATP
Electron Transport Chain (ETC)
The process of creating ATP from:
- ADP
- NADH
- FADH2
Cytochromes
Electron carriers in the Electron Transport Chain
Beta Oxidation
A series of reactions in which Free Fatty Acids are
- Broken Down
- Creates Acetyl-CoA and H-
Total ATP Yield from Oxidation of ONE Glucose Molecule
40
Gluconeogenesis
The process of converting Amino Acids into Glucose
Branched Chain Amino Acids
-Leucine
-Isoleucine
-Valine

Major amino acids that are oxidized in Skeletal Muscle
Total E+ Yield from Oxidation of ONE Triglyceride
463
Exercise Intensity
The Level of Muscular Activity that can be quantified in terms of Power Output
Power
Work performed per:
- Unit of Time
Relationship of Energy Systems
Inverse Relationship between:
- Energy System's max rate of ATP production
- Total amount of ATP production capable
E+ System for 0-6 seconds
(Intensity: Extremely High)
Phosphagen
E+ System for 6-30 seconds
(Intensity: Very High)
Phosphagen/Fast Glycolysis
E+ System for 30 secs - 2 mins
(Intensity: High)
Fast Glycolysis
E+ System for 2-3 minutes
(Intensity: Moderate)
Fast Glycolysis/Oxidative System
E+ System for >3 minutes
(Intensity: Low)
Oxidative System
Energy Substrates
Molecules that provide starting materials for:
- Bioenergetic Reactions
- Includes Phosphagens (ATP/CrP), Glucose, Glycogen, Lactate, Free Fatty Acids, Amino Acids
Time for Post-Ex Phosphagen Replenishment
3-5 mins
Glycogenolysis
Breakdown of Glycogen
Oxygen Uptake (O2 Consumption)
The measure of a person's ability to:
- Take in/Use Oxygen
Oxygen Deficit
The Anaerobic Contribution to the:
- Total E+ Cost of Exercise
Oxygen Debt
Post-Exercise Oxygen Uptake
Excess Postexercise Oxygen Consumption (EPOC)
The Oxygen Uptake:
- Above Resting Values
- Used to restore the body to pre exercise conditions

Factors:
- ATP REsynthesis
- O2 resaturation
- Repair Damage
- Increased body temperature
Metabolic Specificity of Training
The use of Appropriate:
- Ex. Intensities
- Rest Intervals
- Ex. Selection
based on the specific Energy Systems used during competition
Interval Training
A method of training that emphasis:
- Bioenergetic Adaptations
- For more efficient energy transfer
- Within Metabolic pathway
- Using Pre-Determined Intervals of Exercise and Rest Periods
Combination Training (Cross-Training)
Adding Endurance Training to Anaerobic Athletes training to:
- Enhance Recovery
- Due to recovery being Aerobic

*Aerobic Endurance training WILL REDUCE ANAEROBIC TRAINING*
* Especially:
- High Strength
- High Power
Exercise-to-Rest Intervals
Phosphagen:
5-10 secs (1:12 - 1:20)

Fast Glycol:
15-30 secs (1:3 - 1:5)

Fast Glycol/Oxid
1-3 mins (1:3 - 1:4)

Oxidative
>3 mins (1:1 - 1:3)