Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
What is the hallmark of RA?
|
Pannus (synovitis)
|
|
|
Classification of RA looks at 4 different categories, what are they?
|
Joints (# and size)
Serology (RF/aCCP) Acute Phase Reactants Duration of symptoms (>6 weeks) There are 10 possible points, a 6/10 means definite RA |
|
|
RA typically involves _ joints, in what pattern?
|
Shoulder, elbow, wrist, MIPs PIPs, Cervical Spine,
Knee, ankle, MTPs Symmetrical! |
|
|
Note that RA does NOT involve _ or _
|
Spine (except cervical) OR DIPs in hands
|
|
|
Felty's syndrome consists of _
|
a triad of autoimmune disease (typically RA), granulocytopenia, and splenomegaly.
In this syndrome, Ab's are directed against granulocytes |
|
|
CXR reveals a nodule in the lung, biopsy comes back RH (-). what do you suspect?
|
lung cancer...if it was RH (+) it would be a rheumatoid nodule
|
|
|
Of particular importance to an anesthiologist, RA patients are at risk for _
|
C1, C2 subluxation.
(must protect the Cervical spine during anesthesia to avoid compressing the spinal cord) |
|
|
When prescribing DMARDs to a patient with rheumatoid arthritis, how often should you have them come back to the office? Why?
|
~ q 2 months,
Methotrexate has high risk for hepatic and pulmonary toxicity. Pt needs to have lab work done every 8 weeks or so to monitor AST, ALT, and CBC. |
|
|
What should you supplement your patients with if they are on Leflunomide?
|
Folic Acid
|
|
|
What are two examples of TNFF alpha inhibitors?
|
Infliximab and Etanercept.
Infliximab is given via infusion, the others are injections. |
|
|
What must you ask your patients before starting them on a biological agent?
|
If they have been exposed to Hep B or TB.
All these drugs greatly increase the risk for infection, it would be devastating to start someone with latent TB on a biologic agent |
|
|
ACR criteria measures what?
|
ACR remission criteria looks at whether someone is improving
AM stiffness, fatigue, joint pain on ROM, Lower ESR? |
|
|
Anti CCP antibody is highly _ for RA, but not very _
|
specific,
sensitive |
|
|
_ and _ are the most important pro inflammatory cytokines
|
TNFalpha and IL1
|
|
|
Rheumatoid nodules are ALWAYS _ and _. If they are not, then someone made a mistake
|
RF (+) and Anti CCP (+)
(seropositive) |
|
|
RA what is the major feature?
|
Synovitis (pannus)
|
|
|
Still's disease presents with _
|
high spiking fever, and leukocytosis, rash and systemic disease
|
|
|
Pauciarticular variety, young girls who are _ have a risk for uveitis
|
ANA +
|
|
|
OA is the prototype for
|
Non inflammatory arthritis
|
|
|
first line treatment of OA is
|
acetominophen
|
|
|
mucocutaneous involvement is classical in what type of arthritis
|
reactive arthritis
|
