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39 Cards in this Set

  • Front
  • Back
Reactive depression
response to real stimuli such as physical illness, loss of a job, death of a loved one, divorce, or financial difficulties
Endogenous depression
major depression, probably a genetically linked biochemical disorder
Dysthymia
chronically depressed mood or loss of interest in usual activities that is not severe enough or does not last long enough to meet criteria for major depression
MAOIs
indications for use
Treatment of atypical or neurotic depression, agoraphobia
MAOIs
adverse effects
Anticholinergic effects, excessive CNS depression, hepatic toxicity, dry mouth, blurred vision,urinary retention, constipation
MAOIs
Nursing concerns
tyramine-rich foods and certain drugs cause hypertensive crisis. Don't discontinue abruptly.
MAOIs
foods to be avoided
aged cheese, alcoholic beverage, avocados, and guacamole, bananas, caffeine beverages, chocolate in large amounts, raisins, sour cream, soy sauce, and yogurt.
MAOIs
drugs to be avoided
amphetamines, antihistamines, decongestants, TCAs, demerol, and SSRIs
Phenelzine sulfate (Nardil)
MAOIs
Isocarboxazid (Marplan)
MAOIs
Tranylcypromine Sulfate (Parnate)
MAOIs
Why are Tricyclic antidepressants a better choice then MAOIs?
because they have fewer side effects.
Tricyclic Antidepressants
indications for use
major depression, enuresis
Tricyclic Antidepressants
Side Effects
anticholinergic effects, orthostatic hypotension, arrhythmias, impotence. in OD fatal ventricular arrhythmias can occur.
Tricyclic Antidepressants
Contraindications
allergy, caution with heart disease, asthma, schizophrenia, bipolar disorder, narrow angle glaucoma, prostatic hypertrophy, or urinary retention.
Tricyclic Antidepressants
Nursing Concerns
in children and elderly, perform ECG first
Tricyclic Antidepressants
teaching measures
for dry mouth: sip water, suck on lemon drops, sugar free candy, increase fluids and fiber for constipation
Imipramine hydrochloride (Tofranil)
Tricyclic Antidepressants
Amitriptyline hydrochloride (Elavil)
Tricyclic Antidepressants
Clomipramine (Anafranil)
Tricyclic Antidepressants
Doxepin hydrochloride (sinequan)
Tricyclic Antidepressants
Nortriptyline hydrochloride (Pamelor)
Tricyclic Antidepressants
SSRIs
indications for use
depression, OCD, bulimia, PMS, preventing HA, GAD, PTSD
SSRIs
contraindications
allergy, caution with renal or hepatic dysfunction or history of seizures,
SSRI
nursing concern
do not give within 2 weeks of MAOIs, potentially fatal reaction can occur. if dose is missed, return to regular dosing schedule , do not double doses.
SSRI
Nursing concerns
go to ER if symptoms of serotonin syndrome occur, prozac should be discontinued at least 5 weeks before starting MAOI
Fluxetine hydrochloride (prozac)
SSRI
Paroxetine hydrochloride (Paxil)
SSRI
Citalopram(celexa)
SSRI
Fluvox (Luvox)
SSRI
Escitalopram (Lexapro)
SSRI
Wellbutrin
Nursing concerns
equally space dose through the day to decrease risk of seizures, low sexual risk of sexual SE,
Wellbutrin
contraindications
bulimia, anorexia, seizure disorders, MAOI therapy
Which antidepressant is not addicting?
Trazodone Hydrochloride (Desyrel)
Which drug can cause serotonin storm?
Sibutramine (Meridia)
Mood stabilizers
Nursing Concern
lithium blood levels must be monitored to prevent toxicity, monitor PT for fatigue, and weight gain, watch electrolyte level.
Which mood stabilizer has a narrow therapeutic window?
Lithium (Eskalith)
Which mood stabilizer is the best choice during pregnancy?
Lamotigine (Lamictal)
dropout rate in one year maintenance studies?
65-70%