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20 Cards in this Set

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acute pain
uncomfortable or hurtful short-term sensation
chronic pain
uncomfortable or hurtful long-term sensation
nociceptors
pain receptors

free nerve endings located throughout body
Ao fibers
sensory neuron wrapped in myelin

signals sharp, well defined pain
C fibers
unmyelinated sensory neuron

conducts dull, poorly localized pain signals
substance P
neurotransmitter responsible for continuing pain message to other neurons

controls whether or not pain signals will stop or continue to brain
endogenous opioids
chemicals produced naturally w/i body that decrease or eliminate pain

acts similar to morphine

group of neurotransmitters:
- endorphins
- dynorphins
- enkephalins
analgesic
drug used for pain relief

classifications:
*non-narcotic
*narcotic
cyclooxygenase
enzyme responsible for formation of prostaglandins

NSAIDS inhibit these
NSAIDS
drugs that inhibit cyclooxygenase

cyclooxygenase -> resonponsible for formation of prostaglandins -> prostaglandins activate peripheral nociceptors -> nociceptors produce pain
bradykinin
chemical mediator of pain

follows tissue damage
prostaglandin
chemical released after tissue damage

leads to pain, inflammation, etc.
narcotic
drug capable of producing numbness or stupor-like condition

includes opioids
opiates
natural narcotic extracted from poppy seeds

includes morphine & codeine
opioid
natural or synthetic morphine-like substance
mu
type of opioid receptor affecting:
- analgesia
- decreased GI motility
- respiratory depression
- sedation
- physical dependence

activated by:
- pure opioid agonist (morphine & codeine)

- mixed opioid agonist (buprenorphine)
kappa
type of opioid receptor affecting:
- analgesia
- decreased GI motility
- sedation

activated by:
- pure opioid agonist
(morphine & codeine)

- mixed opioid agonist
(pentazocine & butorphanol)
antipyretic
reduces fever
tension headache
muscles of head/neck area become tight

due to stress & tension
migraine
severe headache w/possible symptoms of:
- aura preceding migraine
- nausea
- vomiting
- sensory cues