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____ stimulates fusion of synaptic vesicles with nerve terminal plasma membraine causing ACh release
Ca
Which muscarinic R are excitatory?
1,3,5 - "odd people are exciting"
Which muscarinic R are inhibitory
2,4
Where does Hemicholinium work?
Choline (starting material for ACh) and Na symporter
Where does vesamicol work?
Prevents ACh from entering potential release vessicle
Where does botulinum work?
Prevents exocytosis of vessicle
What enzyme is used for AcCoA + Choline --> ACh
Choline Acetyltransferase
What 3 drugs cause Na channel block?
Tetrodotoxin
Scorpion Toxin
Local Anesthetics
What drugs disrupt ACh synthesis, storage, release, etc (3)
What drugs Act on ACh R (3)
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