term1 Definition1term2 Definition2term3 Definition3
Please sign in to your Google account to access your documents:
what are the origins of antibiotics?Give examples;
Antibiotics are common metabolic products of aerobic bacteria and fungiBacteria: Streptomyces and BacillusMolds: Penicillium and Cephalosporium
Drugs should be ______ ______they kill or inhibit microbial cells without damaging host tissues
selectively toxic
what does the spectrum of an antibiotic mean?
Range of different bacteria affected by Ab
describe:broad spectrumnarrow spectrumlimited spectrum
BROAD SPECTRUM: kill/inhibit wide range of gram+/-NARROW SPECTRUM: kill/inhibit mainly gram+ or gram-LIMITED SPECTRUM: effective against single species
what are the 5 fundamental mechanism of antibiotic action?
Inhibition of cell wall synthesis2: Inhibition of nucleic acid structure and function3: Inhibition of folic acid synthesis (really this is a type NA inhibition)4: Inhibition of protein synthesis5: Interference with cell membrane structure or function
What is the anagram for the 5 fundamental mechs of antibiotic actioN?
Pro (protein synthesis)Members (cell membrane)Follow (folic acid)New (nucleic acid)Wallets (cell wall)
name two antibiotic classes that react to disrupt cell wall synthesis. How?
penicillins and cephalosporinsBlock some aspect of peptidoglycan synthesis
what is a "r"-lactam?
penicillins and cephalosporins - Named for their four membered ring structure
"r"-lactams cause _____ _____ ______
cell wall destruction
what is the spectrum of "r"-lactams?
Some: against gram+/-, others: against either/or
Need help typing ? See our FAQ (opens in new window)
Please sign in to create this set. We'll bring you back here when you are done.
Discard Changes Sign in
Please sign in to add to folders.
Sign in
Don't have an account? Sign Up »
You have created 2 folders. Please upgrade to Cram Premium to create hundreds of folders!