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Temperature
As temperature increases enzymes gain more kinetic energy
Kinetic energy
Enzymes have more kinetic energy so more collisions with substrate
Enzyme collisions
Collisions with substrate increases rate of reaction
Increase rate of reaction until
Optimum temperature
Above optimum temperature enzymes start to denature
Enzymes denature
Active site changes shape
Active site changed shape
Substrate no longer fits
Substrate no fit in active site
Rate of reaction decreases
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