term1 Definition1term2 Definition2term3 Definition3
Please sign in to your Google account to access your documents:
Main function of eccrine glands
thermoregulation through evaporative heat loss, also excrete heavy metals, drugs, organic compounds and macromolecules
Eccrine glands begin to develop at 3 months gestation and gradually appear everywhere by 5 months except for:
External auditory canal
Lips
Clitoris
Labia minora
Glans
Inner prepuce
Nails
So, ears and genitals
Area of the body with:
most eccrine?
least eccrine?
most- palms, soles, axilla
lowest- back
The eccrine secretory unit consists of two segments...
1. Secretory coil- proximal coiled portion in lower dermis
2. Duct- long, thin channel that ends at the acrosyringium
The secretory coil of eccrine glands contain 3 distinct cell types. What are they and what do they do?
1. Clear cells- abundant mitochondria and lipofuscin granules, function in the secretion of water and electrolytes
2. Dark cells- smooth membrane with basophilic granules that produce sialomucin; resorbs Na
3. Myoepithelial cells- contractile cells with actin fibers! envelope both the clear and dark cells and enhance delivery of sweat to the skin; responds to CHOLINERGIC stimulation
What is so important about the eccrine duct and microbes?
The ductal epithelium is composed of 2 layers of cuboidal cells (basal ductal cells and luminal ductal cells) which secrete antimicrobial peptide B defensin!!
The post ganglionic sympathetic fibers of eccrine glands are innervated by what?
acetylcholine
**remember all preganglionics are Acetylcholine... post can either be sympathetic or parasympathetic
3 types of secretion are? What type do eccrine ducts use?
Merocrine- secretion via exocytosis (ECCRINE)
Holocrine- secretion by membrane rupture (SEBACEOUS)
Apocrine- secretion by membrane budding (APOCRINE)
Is our sweat hypertonic, isotonic or hypotonic?
HYPOTONIC! secretion of isotonic sweat by secretory coil in response to cholinergic stimulation, cells along eccrine duct partially reabsorb NaCl resulting in release of hypotonic sweat
**so the faster the flow rate, the less time the duct has to resorb NaCl, the more is secreted in sweat
What is Frey's Syndrome?
Damage to parotid glands and/or auriculotemporal nerve after surgery --> focal hyperhidrosis on damaged side
Need help typing ? See our FAQ (opens in new window)
Please sign in to create this set. We'll bring you back here when you are done.
Discard Changes Sign in
Please sign in to add to folders.
Sign in
Don't have an account? Sign Up »
You have created 2 folders. Please upgrade to Cram Premium to create hundreds of folders!