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157 Cards in this Set

  • Front
  • Back
Name 7 allergens that fall in the fragrance category.
M/C family of allergens = fragrance.
Myroxylon pereirae
fragrance mix 1
fragrance mix 2
cinnamic aldehyde
Ylang ylang oil
jasmine absolute
tea tree oil oxidized
Name the 5 formaldehyde releasing preservatives
2-bromo-2-nitropropane-1,3-diol
diazolidinyl urea
imidazolidinyl urea
DMDM hydantoin
Quarternium 15
M/C cosmetic preservative to cause ACD.
Quarternium 15
Non formaldehyde releaser preservatives (2)
Parabens, MCI/MI
What is MCI/MI
methyl chloroisothiazolinone and methyl isothiazolinone
Kathon GC
Non formaldehyde releaser preservative
Fragrance Mix consists of what?
Cinnamic alcohol
cinnamic aldehyde
hydroxycitronellal
isoeugenol
eugenol
oak moss absolute
alpha amyl cinnamic aldehyde
geraniol
Why are formaldehyde releasers used as preservatives?
increases shelf life
makes it more stable
kills gram negative organisms
What test can be used to see if something has nickel?
dimethylglyoxime test - turns pink if nickel is present
What will neomycin cross react with?
Aminoglycosides

Co-reactivity with bacitracin and neomycin due to consensitization --> they are used together and not chemically related
Name the two steroids used to patch test and their classes.
Tixocortol pivalate (A)
Budesonide (B)
Group A Steroids
Hydrocorisone
Prednisolone
Methylprednisone
What do all the Group B Steroids have in common?
End in -IDE
Budesonide
triamcinolone acetonide
Desonide, etc
Group C Steroids
Betamethasone
Desamethasone
Ophthalmic steroids are usually found in what Group?
Group C
What do Group D steroids have in common?
17-OH steroids
end in -ATE
Cobalt chloride used in what color tattoos?
Blue
Pink (?)
What is found in some implantable devices?
Cobalt
p-tert-butylphoneol formaldehyde resin is what? Where do you find it?
flexible leather glue

belts and wrist watches
P-phyenlyenediamine
hair; henna tattoos
What does PPD cross react with?
azo- and aniline dyes; procaine; benzocaine; PABA; sulfa
Do those who react to quarternium 15 react to formaldehyde?
Yup, in about 80%
Potassium dichromate is seen in what?
tanned leather
cement
match heads
Will those sensitive to Cobalt have a sensitivity to Chromate and Ni?
Yes
Chromate - m/c men
Nickel - m/c women
Carb mix
Thiuram Mix
Mercapto Mix
Mercaptobenzothiazole
Mixed dialkyl thiourea
n,n-diphenylguanidine

Are all what?
Rubber accelerators
Which rubber accelerator is a/w industrial pesticides?
mercaptobenthaziazole
What is found in neoprene rubber (mouse pads; wrist rests; body suits)
mixed dialkyl thiorheas
Black rubber mix cross reacts with?
aka isopropyl PPD
cross reacts with PPD

is a antioxidant for rubber
What medication can you find thiuram mix
antabuse
Where does colophony come from?
pinus palustris and pinus caribaea
aka pine rosin
Colophony found in:
baseball rosin bags; violin bows; mascara; adhesive
Epoxy resin used in what?
Industrial cement - boats and aircraft

is watertight
What is one of the most important industrial allergens?
epoxy resin
Who else uses epoxy?
dentists
What is found in wool alcohol?
lanolin (comes from sheep fleece
M/C presentation of lanolin allergy?
chelitis - lip balm
dermatitis on LE - ulcers or stasis
Commonly used medication that can cause anaphylaxis
Bacitracin
Benzophenone 3 is what?
sunscreen - both UVA and UVB
Common textile allergen
Disperse blue 106 and 124
Disperse blue is found in?
clothes; dark clothes; blended
Common locations of Gold ACD
eyelids; stents; hand derm
T/F - Patients with gold allergy are more likely to be allergic to Co and Ni.
True
Ethyl acrylate
Nail glue;
Compositae and sesquiterpene lactone mix
plants; a/w 20% of those with chronic actinic dermatitis; facial derm that is photodistributed but without submental sparing
Compositae is AKA

Name some items
asteraceae

Artichokes, chrysanthemum, ragweed, sunflower
Allergen of compositae
sesquiterpene lactone
what medication is derived from chrysanthemums

what family are chrysanthemums found?
Elimite

asteraceae/compositae
Tosylamide formaldehyde resin

common presenting location
nail polish

eyelid derm
Where do you methyl metahcrylate?
glue in ortho and teeth
Distribution of ACD in dentist and florists?
1st, 2nd and 3rd fingers
Propylene glycol
solvent, preservative, enhances penetration
What presevative is found in minoxidil?
propylene glycol
cetyl stearyl alcohol commonly found in?
moisturizers
What is sorbitan?
it is a surfactant and emulsifier for cosmetics
Cocamidopropylbetaine/3-dimethylamino propylamine (DMAPA)
surfactants

found in soap
Glyceryl thioglycolate
permanent wave solution
T/F if a woman gets a perm that has glyceryl thioglycolate, it stops being allergenic once you cut it off.
False - it is allergenic for life of hair.
ethyleneurea melamine-formaldehyde resin
textile; formaldehyde releasing clothing - sizing and permanent press
iodopropynyl butylcarbamate
non formaldehyde releaser - presvative
chloroxylenol (PCMX) and 4-Chloro-3-cresol (PCMC)
biocides - hand soap - sterilizing instruments
Pattern for glutaral dermatitis and where found?
unilateral pattern on face

GI/Sterilizing/Dental
What is found in crazy glue and dermabond?
ethyl cyanoacrylate
What allergen is associated to babies dying in the NICU?
benzyl alcohol

used as a preservative for IV fluid/Normal saline
benzalkonium chloride
baby wipes and eyedrops
Found in most ophtho preps?
benzalkonium chloride
What is methyldibromoglutaronitrile?
non formaldehyde releaser

**M/C to cause CD
Associations with propolis
Bees; cosmetics
n,n-diphenylguanidine
rubber accelerator
Common personal hygiene product that contains triethanolamine.
Shaving cream - emulsifier and surfactant
Amidoamine is what?

Includes?
surfactant

olemaidopropyl dimethlamine/cocamide DEA
What is in hibiclens?
chlorhexidine digluconate
What is phenoxyethanol?
non formaldehyde releaser
BHT
2,6 ditert butyl 4 cresol
Where is BHT found?
cosmetics; hydroquinone; cereal
Di alpha tocopherol
vitamin e; antioxidant
What is cocamide DEA used for/
Foaming agent
Triclosan
Lever; toothpaste; mouthwashes
What does thimerosal cross react with?
mercury; piroxicam
Balsam of peru comes from?
myroxylon pereirae tree
Where is balsam of peru found naturally?
tomatoes; citrus; cola
Besides henna and hair dyes, where else is PPD found?
inks; photodeveloping solutions; dyes
alliaceae
garlic, onions and chives
What is the most important allergen in garlic?
diallyl disulfide
alsteromeriaceae and liliaceae
peruvian lily and tulips
Allergen in toxicdendron
urushiol
families of plants a/w phytophoto
fucomarins
a celery fennel parsnip
m fig tree
r citrus
tea tree oil comes from what plant?

allergen?
melaleuca

d-limonene
Latex allergy cross reactors
banana, avocado, chestnut and kiwi
Solanaceae
capsaicin; neutralized with vinegar
Found in shampoos?
Cocaimdopropyl betaine
surfactant
Alkalis
Irritant CD
Destroy keratin so can penetrate deeply
Soaps detergents, lye
Acids
Corrosive causing burns
Treat with copious water and neutralize with sodium bicarb
What helps fiberglass fibers slide out?
Talcum powder
What is found in pepper spray?
Capsacin; use acetic acid to neutralize
Locations of chloracne
malar crescent, ear lobes, retroauricular area, neck, shoulders, and scrotum
Toxicodendron cross reactors
Poison oak, ivy, sumac
Cashew nut tree
Japanese Lacquer Tree
Mango rind and sap
Rengas Tree
Indian marking nut tree
Gingko
Allergen in toxicodendron
uroshiol
What kind of gloves protect from uroshiol?
vinyl gloves
Most common allergy in florists
tuliposide A
Alstromeria "Peruvian lily"
Primrose
Compositae asteracaea
Sesquiterpene lactone
Is phytophyto photoallergic or phototoxic?
How long after exposure?
phototoxic
after 24 hours usually
Phytophoto on your ARM
Apiacea - celery, parnip, parsley, dill, carrot, hogweed, and fennel
Rutaceae - citrus, lime, lemon, lei flowers
Moracea - fig tree levaes
St. John's wart
Daffodil leads to what?
irritant CD due to calcium oxalate
What plants have irritant as calcium oxalate?
Daffodil, araceae, pineapple
Bleached underwear band
dibenzyldithiocarbamate
Formaldehyde releasers
2,5 diazolidinylurea
2-bromo-2-nitropropane-11,3 diol bronopol
imidazolidinylurea
Q15
DMDM hydantoin
Rubber rubber accelerators
mercaptobenzothiazole
Adhesive for shoes
P tert butylphenol formaldehyde for glue for leather
Tanned leather
Potassium dichromates
Foam padding athletic shoes
diisocyanates
Thiuram
#1 gloves, #2 shoes
Mercury
Thimerisol in vaccines
What blocks nickel (ion?)
Vitamin C
Found in cement workers, tanners, painters, photographers
hexachromates
wet cement, green dye, zippers, shoe leather
Associated with Vitamine B12
Cobalt (as well as blue tattoo)
Main component of rubber gloves
thiuram
Allergy to neoprene
diakyl thioureas
Bleach does what?
It sensitizes rubber making it a sensitizer
Resin dermatitis - T/F liquid form is not sensitizing?
False causes severe reaction; polymerized form is not sensitizing
Polyester resins
Sculptors, helmets, lamp shades, and boat hulls
Causes purpuric CD; does this penetrate latex
PPD; yes it does penetrate latex
Hair Bleach
ammonium persulfate
permanent Hair waves
glyceryl monothioglycolate
Nail products
tosylamide formaldehyde resin
acrylic nails

Monomer is allergenic T/F
acrylates; also peripheral neuropathy

T - Only monomer is allergenic S2 epoxy resins
BOP - avoid what?
rosin from South American tree
Avoid eugenol, tomato, citrus, benzoin, colophony
Preservatives - non formaldehyde releasing
parabens
MCI
Thiomerosal
Found in break fluid, food, cosmetics
propylene glycol
What does ethylene diamine do?
stabilizes medication creams; x reacts with atarax
Thickening foaming
propyl gallate
PABA allergic - avoid:
thiazides
sulfonylureas
PPD
benzocaine (esters)
azodyes
Most common photocontact allergen in US?

what does it cross react with?
oxybenzone

ketoprofen and fenofibrate
Where does BOP come from?
myroxylon perirae
What does BOP cross react with?
cinnamon, vanilla, citrus, sweets, cola, benzoin, liquor
What is geraniol?
rose
Tooth paste allergen?
cinnamic aldehyde
Lemon allergens
psoralens, geraniol, citral, d limonene
Can hairdressers get ACD from permanent wave allergen?

How about for PPD?
glyceryl monothioglycolate - Yes, they can

PPD allergic hairdressers cannot
Most common abx to cause anaphylaxis?

What is it coreactive with? and what is its MOA?
bacitracin

Neomycin; inhibits cell wall synthesis
Neomycin is what?

what is its MOA?
MC topical abx reaction with chronic OE
inhibits bacterial protein synthesis by irreversibly binding to 30s ribosome SU; G neg
MC three agents used to patch test for topical steroid allergy?
Tixocortol pivalate
budesonide (B)
HC butyrate

**Fails to ID 3/4 of patients with allergy to clobetasol or betamethasone (class D)
Comes from sebum of sheep
lanolin
What other allergen is found in aquaphor and what is it?
bisabolol - is a sesquuiterpene alcohol that cross reacts with compositae and sesquiterpene lactone
M/c sources of acrylates?
Dentists
Acrylic nails
adhesives
tissue adhesive
hearing aids
Hearing aids associated with what?
acrylates
Allergy to asteracea should avoid what medication?
elimite - derived from chrysanthemums
Tulip bulbs cause
irritant CD (fissure eczema on grip area of fingers)
MCC of irritant CD in florists
calcium oxalate
Garlic allergen
diallyl disulfide
Found in violin bows, adhesive, gum, glossy paper?
colophony, rosin
Comes from pine trees
Xreacts with BOP
Where is latex derived from?

Which products have higher protein levels?
Hevea brasiliensis

Thin stretchy products like balloons condoms, gloves NOT paint
MC used preservative in cosmeticcs
Parabens - low rate of sensitization
Nickel allergy test
dimethylglyoxime test - turns pink when rubbed
If nickel negative patch test with nickel like dermatitis
think cobalt
What is the more common cause of clothing aCD than formaldehyde?
Disperse Blue Dye
Shoe Glue
P tert butyl phenol formaldehyde
colophony
Shoe leather
potassium dichromate
rubber accelerator
thiuram mix;
mercaptopbenzothiazole