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6 Cards in this Set

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Fentanyl

mechanism of action
Mechanism Of Action: binds to various opiate receptors, producing analgesia and sedation (opioid agonist)

Pregnancy: C
Lactation: Safe
Metabolism: liver; CYP450: 3A4 substrate
Excretion: urine (10-25% unchanged); Half-life: 3.7h
DEA/FDA: Schedule II

Class: Induction/Maintenance
Alfentanil

Mechanism Of Action
Mechanism Of Action: binds to various opiate receptors, producing analgesia and sedation (opioid agonist)

Pregnancy: C
Lactation: Probably Safe
Metabolism: liver extensively; CYP450: 3A4 substrate
Excretion: urine (<1% unchanged); Half-life: 1.5-1.8h
DEA/FDA: Schedule II

Class: Induction/Maintenance, Narcotics
Sufentanil

Mechanism Of Action
Mechanism Of Action: binds to various opiate receptors, producing analgesia and sedation (opioid agonist)

Pregnancy: C
Lactation: Safety Unknown
Metabolism: liver, small intestine; CYP450: 3A4 substrate
Excretion: urine (<2% unchanged); Half-life: 2.7h
DEA/FDA: Schedule II

Class: Narcotics, Induction/Maintenance
Remifentanil

Mechanism Of Action
Mechanism Of Action: binds to various opiate receptors, producing analgesia and sedation (opioid agonist)

Pregnancy: C
Lactation: Safety Unknown
Metabolism: other
Excretion: urine
DEA/FDA: Schedule II

Class: Narcotics, Induction/Maintenance
Meperidine

Mechanism Of Action
Mechanism Of Action: binds to various opiate receptors, producing analgesia and sedation (opioid agonist)

Pregnancy: C
Lactation: Safety Unknown
Metabolism: liver; CYP450: 2D6 substrate; Info: active metabolite
Excretion: urine; Half-life: 2.5-4h (adults), 23h (neonates); 15-30h (normeperidine); Info: active metab. accumulation in renal or hepatic impairment assoc. w/seizures
DEA/FDA: Schedule II

Class: Narcotics
Morphine

Mechanism Of Action
Mechanism Of Action: binds to various opiate receptors, producing analgesia and sedation (opioid agonist)

Pregnancy: C
Lactation: Probably Safe
Metabolism: liver
Excretion: urine
DEA/FDA: Schedule II

Class: Narcotics