Cns4 - Tumors Of The Cns

Front 1

What are the 2 broad categories of CNS tumors?

Back 1

-Primary
-Secondary

Front 2

What are Primary CNS tumors?

Back 2

Those that derive from the CNS parenchyma and coverings - INTRINSIC

Front 3

What are Secondary CNS tumors?

Back 3

Those that are metastasized from a primary site elsewhere. Extrinsic

Front 4

What are 2 ways of classifying intrinsic tumors histologically?

Back 4

-Based on histologic elements seen normally in the nervous system
-Based on Embryonal elements

Front 5

What are 3 glial cells that are normally found in the nervous system?

Back 5

-Astrocytes
-Ependymal cells
-Oligodendrocytes

Front 6

What are 2 terms for a tumor of astroyctes?

Back 6

-Astrocytoma
-Glioblastoma

Front 7

What are 3 types of tumors of ependymal cells?

Back 7

-Ependymoma
-Choroid plexus papilloma
-Colloid cyst

Front 8

What is a tumor of oligodendrocytes called?

Back 8

Oligodendroglioma

Front 9

What does a glioma in the usual sense refer to?

Back 9

Tumors of astrocytes, ependymal cells, or oligodendroctyes

Front 10

What does a glioma in the BROAD sense refer to?

Back 10

Tumors of astrocytes, ependymal cells, or oligodendroctyes AND Tumors of neuronal cells and primitive bipotential precursors

Front 11

What are 5 tumors of neuronal cells and primitive bipotential precursors?

Back 11

-Medulloepithelioma
-Medulloblastomas
-Retinoblastomas
-Neuroblastomas
-Ganglioneuromas and gangliogliomas

Front 12

What is a tumor of pineal cells called?

Back 12

Pinealoma

Front 13

What is a tumor of Microglia called?

Back 13

Lymphoma of the CNS

Front 14

What is a tumor hypophyseal cells called?

Back 14

Pituitary adenoma

Front 15

What is a tumor of arachnoidal cells called?

Back 15

Meningioma

Front 16

What is a tumor of Schwann cells or endoneurial cells called?

Back 16

Schwannoma or neurofibroma

Front 17

What are 3 terms for tumors of connective tissue cells?

Back 17

-Hemangioblastoma
-Fibroma
-Sarcoma

Front 18

What is a tumor of melanocytes?

Back 18

Melanoma

Front 19

What are 5 embryonal cell types that can form tumors in the CNS?

Back 19

-Epithelial tissue
-Notochordal cells
-Adipose cells
-Germ layer cells
-Mixed embryonal cells

Front 20

What are 2 types of tumors with embryonal elements of epithelial tissue?

Back 20

-Craniopharyngioma
-Cholesteatoma

Front 21

What is a tumor of notochordal cells?

Back 21

Chordoma

Front 22

What is a tumor of adipose cells?

Back 22

Lipoma

Front 23

What are 3 types of nervous system tumors made up of cells from germ layers?

Back 23

-Epidermoid cysts
-Dermoid cysts
-Teratoma

Front 24

What are 2 names for mixed embryonal cell tumors?

Back 24

-Atypical teratoid
-Rhabdoid tumor

Front 25

What are 2 main categories of extrinsic tumors?

Back 25

-Those from the skull/spine
-Those from other body areas

Front 26

What are 4 extrinsic tumors that originate from the skull/spine?

Back 26

-Osteoma
-Sarcoma
-Chondroma
-Myeloma

Front 27

Other than intrinsic/extrinsic or histology, how do we classify nervous system tumors?

Back 27

Based on location

Front 28

What are the 2 broad categories of nervous system tumors based on location?

Back 28

-Intracranial
-Intraspinal

Front 29

2 types of intracranial tumors:

Back 29

-Supratentorial
-Infratentorial

Front 30

2 subtypes of supratentorial tumors:

Back 30

-Cerebral hemisphere tumors
-Sella turcica tumors

Front 31

What are 3 tumors that are commonly found in the cerebral hemispheres?

Back 31

-Gliomas
-Meningiomas
-Metastatic tumors

Front 32

What are the 2 tumors commonly found at the Sella turcica?

Back 32

-Pituitary adenomas
-Craniopharyngiomas

Front 33

What are 2 subcategories of infrantentorial tumors?

Back 33

-Cerebellopontine angle tumors
-Midline tumors

Front 34

What type of tumor is found at the cerebellopontine angle?

Back 34

Schwannomas

Front 35

What are 4 infrantentorial midline tumors?

Back 35

-Brainstem gliomas
-Ependymomas
-Medulloblastomas
-Hemangioblastomas

Front 36

What do intraspinal tumors refer to?

Back 36

Those inside the spinal canal and adjacent spinal vertebrae

Front 37

What are 2 subcategories of intraspinal tumors?

Back 37

-Extradural
-Intradural

Front 38

What are Extradural Intraspinal tumors further divided into?

Back 38

-Spinal tumors
-Epidural tumors

Front 39

What are spinal tumors often derived from?

Back 39

Vertebral metastases and bone tumors

Front 40

What do Epidural tumors tend to be?

Back 40

Metastases

Front 41

What are 2 types of Intradural intraspinal tumors?

Back 41

-Extramedullary (outside SC)
-Intramedullary (inside SC)

Front 42

What are 3 extramedullary intradural intraspinal tumors?

Back 42

-Neurofibroma
-Schwannoma
-Meningioma

Front 43

What are 3 intramedullary intradural intraspinal tumors?

Back 43

-Ependymoma
-Astrocytoma
-Glioblastoma

Front 44

What is the incidence of primary CNS tumors in all autopsies? What % of all primary tumors in general?

Back 44

1.2% of autopsies
9% of all primary tumors

Front 45

What % of all intracranial tumors are metastatic? What trend is seen in these?

Back 45

15-50% - increasing incidence

Front 46

What are the two most common intracranial tumors in all patients?

Back 46

-Gliomas
-Metastatic tumors

Front 47

What is the most common type of intracranial glioma at any age? What is second most common?

Back 47

Glioblastoma 55%
Astrocytoma 21%

Front 48

What are the 3 most common intracranial gliomas in children?

Back 48

Astrocytomas 48%
Medulloblastomas 44%
Ependymomas 8%

Front 49

Where are intracranial tumors predominantly located in
-adults
-children

Back 49

Adults - supratentorial
Children - infratentorial