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49 Cards in this Set
- Front
- Back
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3 types of cerebral edema
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vasogenic
cytotoxic interstitial |
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cerebral edema that is tx w/ steroids
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vasogenic
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cerebral edema that increase intracellular water
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cytotoxic
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stage or grade is important in CNS tumor
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grade
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tumor with high rate of mets to brain
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choriocarcinoma
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grade I astrocytoma
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pilocytic astrocytoma
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grade II astrocytoma
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diffuse infiltrating
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grade III astrocytoma
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anaplastic
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grade IV astrocytoma
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GBM
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most common infratentorial tumors of children
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pilocytic astrocytoma
medulloblastoma |
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cystic tumor w/ a mural nodule
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pilocytic astrocytoma
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most common location of pilocytic astrocytoma
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cerebellum
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(+) rosenthal fibers w/ hair like cytoplasmic processes
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pilocytic astrocytoma
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adult CNS tumor w/ a mutated form of p53
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diffuse infiltrating astrocytoma
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most frequent primary brain tumor in adults
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giloblastoma multiforme (GBM)
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two types of GBM
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primary (de novo)
secondary (progressed from lower grade) |
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type of GBM seen in younger pt.
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primary
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type of GBM seen in older pt.
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secondary
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GBM tumor with EGFR mutation
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primary (easier to treat)
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deletion of chromosome 1p/19q
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oligodendroglial tumor (susceptible to chemo)
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grade II oligodendroglial tumor
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oligodendroglioma
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grade III oligodendroglial tumor
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anaplastic
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chicken wire vasculature
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oligodendroglial tumor
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fried egg cytology
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oligodendroglial tumor
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adult CNS tumor with calcifications
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oligodendroglial tumor
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tumor with bimodal distribution of age
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ependymoma
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most common location of ependymomas in children
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4th ventricle
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most common location of ependymoma in adults
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spinal cord
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true and pseudorosettes
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ependymoma
medulloblastoma |
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benign tumor that occurs in the lateral ventricles of children
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choroid plexus papilloma
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tx of medulloblastoma
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xrt (w/ surgery)
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mutation in NF2 gene of chromosome 22 in CNS
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meningioma
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CNS tumor that is rare unless pt. is immunocompromised
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lymphoma
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most lymphomas are of what origin
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B cell
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primary germ cell tumor of the brain
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germinoma
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non-neoplastic PNS tumor assx with trauma
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neuroma
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PNS tumors that are grade III or IV
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malignant peripheral nerve sheath tumors (MPNST)
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encapsulated PNS tumor
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schwannoma
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PNS tumor with mutation in NF2
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bilateral vestibular schwannoma
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pt. presents with tinnitus and balance problems
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bilateral vestibular schwannoma
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unencapsulated PNS tumor that infiltrates the nerve
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neurofibroma
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most common form of neurofibromatosis
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type I (von recklinghausen)
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mutation in chromosome 17
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NF1 (von recklinghausen)
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type of neurofibromatosis with assx skin conditions
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type I
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most cases of MPNST occur from progressed what
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NF1
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PNS tumor with poor prognosis
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MPNST
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Ab against Ca channels in sk. muscle that occurs in the context of small cell lung carcinoma
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labert-eaton
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(+) anti-yo
(+) anti-hu |
limbic encephalitis (paraneoplastic syndrome)
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CNS tumor with poor prognosis
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>grade III astrocytoma
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