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24 Cards in this Set
- Front
- Back
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ketorolac (indoleacetic acid derivative)
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only NSAID that can be taken parenterally
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Arylpropionic acids (ibuprofen and Naproxin)
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competitive inhibitors of COX 1 and COX 2
lower GI toxicity safe in Peds and pregnant |
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choline magnesium trisalicylate
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treatment for rheumatoid arthritis
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sulfasalazine
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treats irritable bowel syndrome
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methylsalcylate
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topical ointment
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indomethacin
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treatment for oncology fevers
neonatal closure of patent ductus arteriosus |
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N-acetylcysteine
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sulfhydryl donor to glutathione for treating acetaminophen overdose
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mirtazepine
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atypical antidepressant
increases the release of norepinephrine and serotonin side effects: sedation and weight gain |
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bupropion
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atypical antidepressant
increases norepinephrine and dopamine activity also good for smoking cessation |
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trazodone
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atypical antidepressant
serotonin antagonist |
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SNRIs
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duloxetine, venlafaxine
inhibit norepinephrine and serotonin re-uptake Toxicity: anticholinergic, sedation, and hypotension |
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duloxetine
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SNRI
inhibit norepinephrine and serotonin re-uptake Toxicity: anticholinergic, sedation, and hypotension |
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venlafaxine
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SNRI
inhibit norepinephrine and serotonin re-uptake Toxicity: anticholinergic and sedation |
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carbamazepine
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- treats bipolar
- inhibits rapid firing of action potentials by blocking Na channels -Side Effects: diplopia (double vision), ataxia (lack of muscle coordination), suicidal thoughts |
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lamotrogine
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treats bipolar and anticonvulsant
- blocks Na channels and Ca channels and inhibits the release of glutamate - good for long-term treatment - safest for preggos with bipolar -side effects: nausea, dizziness, headache, rash in peds, suicidal thoughts |
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valproic acid
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- treats bipolar and anticonvulsant
- inhibits firing by blocking Na channels - reduces Ca current -side effects: GI, weight gain, alopecia, suicidal thoughts |
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acetaminophen (APAP)
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- active metabolite of phenacetin
- weak inhibitor of COX-1 and COX-2 - no anti-inflammatory properties - glucuronation and P-450 metabolism - renal failure - safe in pregnant |
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celecoxib
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- inhibits COX-2 mainly
- approved for osteoarthritis, acute pain, and menstrual - cardiovascular risks! |
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acetylsalicylic acid (aspirin, ASA)
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- inhibits COX-1 and COX-2
- adverse: GI due to COX-1 inhibition - overdose: TRIAD of tinnitus, respiratory alkalosis, and metabolic acidosis - Reyes: hepatic injury in peds - Triad asthma: asthma, nasal polyps, and hypersensitivity which is non-immune related - uricosuric: messes with gout - prolonged bleeding pregnant: only for sever arthritis |
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atypical anti-psychotics (olanzapine, risperidone, quetiapine, ziprasidone)
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- treats bipolar and mania
- dopamine receptor agonist - possibly serotonin and/or norepinephrine activity - side effects: drowsy, dizzy, diplopia, sun sensitivity, rash, menstrual problems - weight gain: leads to metabolic syndrome tardive dyskinesia (mouth muscle movements) |
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olanzapine
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- atypical anti-psychotic
- treats bipolar and mania - dopamine receptor agonist - possibly serotonin and/or norepinephrine activity - side effects: drowsy, dizzy, diplopia, sun sensitivity, rash, menstrual problems - weight gain: leads to metabolic syndrome tardive dyskinesia (mouth muscle movements) |
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risperidone
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- atypical anti-psychotic
- treats bipolar and mania - dopamine receptor agonist - possibly serotonin and/or norepinephrine activity - side effects: drowsy, dizzy, diplopia, sun sensitivity, rash, menstrual problems - weight gain: leads to metabolic syndrome tardive dyskinesia (mouth muscle movements) |
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quetiapine
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- atypical anti-psychotic
- treats bipolar and mania - dopamine receptor agonist - possibly serotonin and/or norepinephrine activity - side effects: drowsy, dizzy, diplopia, sun sensitivity, rash, menstrual problems - weight gain: leads to metabolic syndrome tardive dyskinesia (mouth muscle movements) |
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ziprasidone
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- atypical anti-psychotic
- treats bipolar and mania - dopamine receptor agonist - possibly serotonin and/or norepinephrine activity - side effects: drowsy, dizzy, diplopia, sun sensitivity, rash, menstrual problems - weight gain: leads to metabolic syndrome tardive dyskinesia (mouth muscle movements) |
