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13 Cards in this Set
- Front
- Back
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What is the most common intracranial neoplasm in adults?
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metastases
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What is the most common primary CNS neoplasm in adults?
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Astrocytoma
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Where do astrocytomas arise?
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Cerebral hemispheres
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What has the worst prognosis among astrocytomas?
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GBM (90% die within 3 months) and survival beyond 2 years is rare
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How do astrocytomas typically appear and spread in the brain?
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Infiltrate brain and have indistinct boundaries, tend to spread along white matter tracts and may cross corpus callosum into the opposite hemisphere.
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Which CNS tumor:
-Has a peak occurrence 40-50 years -Is malignant, but has a more indolent progression than fibrillary astrocytomas -Patients survive up to 10-15 years after presentation |
Oligodendrogliomas
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What is the differential for a ring-enhancing brain lesion?
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Mets, abscess, GBM, lymphoma, toxo
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What CNS neoplasm:
--Is related to immunosuppression, especially in organ transplants and AIDS, --Median duration of survival <2 years, 5-year survival <5%? |
Primary lymphomas
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What are the most common primary sites of neoplasms that metastasize to the brain?
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(In order of occurrence)
Lung, breast, skin (malignant melanoma), kidney, GI tract |
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What are the 4 main intraparenchymal brain tumors?
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Astrocytomas, oligodendrogliomas, primary lymphomas and metastatic brain tumors
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What are the 2 main extraparenchymal brain tumors?
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Meningiomas and schwannomas
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Which CNS neoplasm:
--Usually occurs between 40-50 years, twice as common in females --Are attached to the dura and compress the underlying brain --Are benign, but may cause morbidity/mortality due to compression --Potential for surgical cure, but high rate of recurrence |
Meningiomas
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What CNS neoplasm is:
--A benign tumor with no malignant potential --Almost always unilateral *What is it if it's bilateral? --Arise in cerebellopontine angle (so involve CN8 but may grow to affect CN5 and 7) --Hearing loss first symptom, then tinnitus, etc. --Surgical excision very good results. Curable if completely removed. |
Schwannomas
B/l = neurofibromatosis type II |
