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14 Cards in this Set

  • Front
  • Back
Polymicrobial abscess: symptoms
headache, drowsiness, confusion, hemiparesis, seizure, fever
Usuall NOT a stiff neck
Polymicrobial abscess: diagnosis
CT scan FIRST
4-5 days: abscess surrounded with fibrous capsule
Ring-enhancing appearance on CT
Polymicrobial abscess: E/P
50% polymicrobial
Streptococcus most common
AIDS pts: toxoplasma & cryptococcus
Cryptococcus neoformans: VF
CHRONIC MENINGOENCEPHALITIS
FUNGAL
Localized in lungs or disseminate
capsule
melanin: protects against macrophages
phospholipase B: degrades host phospholipids
Urease
Cryptococcus neoformans: E/P
CHRONIC MENINGOENCEPHALITIS
FUNGAL
Aquisition: inhalation
distribution: pigeon poop, rotting wood
Cryptococcus neoformans: Clin ID
CHRONIC MENINGOENCEPHALITIS
FUNGAL
Gram positive yeast
India ink positive
Calcoflour White positive
urease positive
capsular Ag
Coccidiodes imitis: VF
CHRONIC MENINGOENCEPHALITIS
FUNGAL
Valley Fever
Transform to spherule in lung
Outbreaks occur after earthquakes, excavation, dust storms
Coccidiodes imitis: P/E
CHRONIC MENINGOENCEPHALITIS
FUNGAL
Valley Feve
Acute resp infection 7-21 days afer exposure, resolves rapidly
inhaled, person --> person
flu-like symp
1% spread to CNS
Histoplasma capsulatum: P/E
CHRONIC MENINGOENCEPHALITIS
FUNGAL
North American Histoplasmosis
Macroconidia from soil
Can disseminate to CNS
Found in bird and bat droppings
Can be confused with TB
Trypanosoma cruzi: Clinical parameters
CHRONIC MENINGOENCEPHALITIS
PARASITE
From bit of triatome bug
South America
Sore--> fever& acute encephalitis
Plasmodium falciparum: Clin parameters
CHRONIC MENINGOENCEPHALITIS
PARASITE
Malaria
From mosquito
fever, chills, anemia
can travel to CNS
fatal fast
How do microbes transverese BBB or B-CSF barrier?
Infecting cells of barrier
Passive transport in intracellular vacuoles
Carried across by WBC
Most common cause of ring-enhancing lesions in AIDS pt?
Toxoplasma gondii
What causes most encephalitis?
Viral infection of the brain