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100 Cards in this Set

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Phenobarbital
Barbiturate; PO, long-acting anti-convulsant; Sched II-III
Holds GABA(A) Cl- channel open independant of GABA; CNS depressant; Sedation->Hypnosis -> anesthetic ->coma ->death
Low Safety Margin: Decr resp. drive, drug of abuse
Supra additive w/ EtOH
Thiopental (Pentothal)
Barbiturate; PO short-acting; used to induce anesthesia, Sch II-III; induces CYP-450
CNS depressant 10-22hrs
Dependance; w/d -> siezures, death
Pentobarbital
Barbiturate
Secobarbital
Barbiturate
Diazepam (Valium)
BZD: ^GABA (ceiling, safer), PO or IV, CYP 3A4, VERY long-acting , 95% PBP
Anticonvulsant, sedative, muscle relaxnt(injuries, EtOH w/d, seizures, convulsions)
Chlordiazepoxide (Librium)
Benzodiazepine; PO, long-acting, t1/2 43hrs +24hrs (metabolites)
Tx seizures, EtOH w/d, convulsions
Flurazepam (Dalmane)
Benzodiazepine: long-acting = t1/2 72hrs!
insomnia
Midazolam (Versed)
Benzodiazepine: short-acting = t1/2 2hrs
Temazepam (Restoril)
Benzodiazepine
insomnia
Triazolam (Halcion)
Benzodiazepine
Very short-acting, insomnia
Alprazolan (Xanax)
Benzodiazepine: t1/2 12hrs
Antidepressant + antianxiety
Lorazepam (Ativan)
Benzodiazepine
Anticonvulsant
Etazolam
Benzodiazepine
Chlorazepate
Benzodiazepine
Oxazepam
Benzodiazepine
Flumazenil (Romazicon)
Benzodiazepine antagonist
Zolpidem (Ambien)
Sleeping sedative
Zaleplon (Sonata)
Sleeping sedative
short-acting, least affect on REM sleep
Eszopiclone (Lunesta)
Sleeping sedative
Longer acting, for chronic insomnia
Buspirone (BuSpar)
Anti-anxiety
5HT agonist, Tx anxiety w/o sedation, safe, 2wks for effect
Chloral Hydrate
anti-histamine sedative via H1
Has tolerance, depend, liver tox
Low MOS, still used on Peds Dental procedures
Disulfiram (Antabuse)
Alcohol Withdrawal
Incr acetylaldehyde & hangovers
Ethanol
Alcohol
Phenytoin (Dilantin)
Alcohol Withdrawal
Naltrexone (ReVia)
Alcohol Withdrawal
Blocks DA reward path
Acamprosate (Campral EC)
Alcohol Withdrawal
Restores NT balance
incr GABA receptors & decr NMDA receptors (norm GABA & Glutamate transmission
Fomepizole (Antizol)
Tx Methanol, Ethylene Glycol
Inhibit metabolism (AD)
Amitriptyline (Elavil)
Tertiary Amine, TCA
Imipramine
Tertiary Amine, TCA
Trimipramine
Tertiary Amine, TCA
Doxepine
Tertiary Amine, TCA
Clomipramine
Tertiary Amine, TCA
Nortriptyline (Pamelor)
Secondary Amine, TCA
Class defining
Desipramine
Secondary Amine, TCA
Protriptyline
Secondary Amine, TCA
Phenelzine (Nardil)
MAOI
Tranylcypromine
MAOI
Fluoxetine (Prozac)
Selective Serotonin Reuptake Inhibitor (SSRI)
Paroxetine (Paxil)
SSRI
Sertraline (Zoloft)
SSRI
Citalopram (Celexa)
SSRI
Escitalopram (Lexapro)
SSRI
Fluvoxamine
SSRI
Duloxetine (Cymbalta)
Antipressant
Bupropoin (Wellbutrin)
Antidepressant
Venlafaxine
Antipressant
Mirtazapine
Antipressant
Atomoxetine
Antipressant
Maprotiline
Antipressant
Amoxapine
Antipressant
Trazodone
Antipressant
Chlorpromazine (Thorazine)
Phenothiazine
Thioridazine (Mellaril)
Phenothiazine
Flupenazine
Phenothiazine
Prochlorperazine
Phenothiazine
Trifluoperazine
Phenothiazine
Thiothixene
Thioxanthene
Haloperidol (Haldol)
Butyrophenone
Clozapine (Clozaril)
New atypical antipsychotic
Risperidone (Risperdal)
New atypical antipsychotic
Ziprasidone (Geodon)
New atypical antipsychotic
Olanzapine (Zyprexa)
New atypical antipsychotic
Quetiapine (Seroquel)
New atypical antipsychotic
Aripiprazole (Abilify)
New atypical antipsychotic
Loxapine
New atypical antipsychotic
Molindone
New atypical antipsychotic
Pimozide
New atypical antipsychotic
Lithium
Mood stabilizer
Divalproex (Depakote)
Mood stabilizer
Valprioc Acid
Mood stabilizer
Gabapentin
Mood stabilizer
Lamotrigone
Mood stabilizer
Carbamazepine
Mood stabilizer
Morphine
Strong Opioid Analgesics
Hydrocodone (Codan)
Strong Opioid Analgesics
Oxycodone (Oxycontin)
Strong Opioid Analgesics
Methadone (Dolophine)
Strong Opioid Analgesics
Meperidine (Demerol)
Strong Opioid Analgesics
Fentanyl (Sublimaze)
Strong Opioid Analgesics
Alfentanil (Alfenta)
Strong Opioid Analgesics
Hydromorphone
Strong Opioid Analgesics
Oxymorphone
Strong Opioid Analgesics
Sufentanil
Strong Opioid Analgesics
Remifentanil
Strong Opioid Analgesics
Levorphanol
Strong Opioid Analgesics
Heroin
Strong Opioid Analgesics
Codeine
Moderate Opioid Analgesics
Propoxyphene (Darvon)
Moderate Opioid Analgesics
Diphenoxylate / atropine
Moderate Opioid Analgesics
Loperamide
Moderate Opioid Analgesics
Buprenorphine (Buprenex)
Mixed angonist-antagonist analgesic
Pentazocine (Talwin)
Mixed angonist-antagonist analgesic
Nalbuphine
Mixed angonist-antagonist analgesic
Butorphanol
Mixed angonist-antagonist analgesic
Dezocine
Mixed angonist-antagonist analgesic
Tramadol (Ultram)
Mixed angonist-antagonist analgesic
Dextromethorphan (Robitussin)
Antitussives
Naloxone (Narcan)
Antagonists
Naltrexone (ReVia)
Antagonists
Nalmefene
Antagonists