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22 Cards in this Set

  • Front
  • Back

Morphene

Opiate Receptor Agonist




-agonist at every receptor subtype


-prototype agonist

Fentanyl

Opiate Receptor Agonist




-very similar to Morphine

Meperidine

Opiate Receptor Agonist




-weak antitussive


-weak anti-diarrheal


-weak effect on uterus (relieves pain w/o prolonging labor)




-IM administration


-slower development of tolerance & dependance


-withdrawal shorter and less severe

Oxycodone

Opiate Receptor Agonist




-very similar to morphine


-well absorbed orally


-addictive potential

Hydrocodone

Opiate Receptor Agonist




-not available in the US




-very similar to Morphine

Hydromorphone

Opiate Receptor Agonist




-very similar to Morphine

Methadone

Opiate Receptor Agonist




-used in Heroin treatment


-analgesic, sedative


-less constipation


-effective orally


-long duration of action

Buprenophine

Opiate Receptor Agonist




-more potent than morphine for mild to medium pain


-Morphine-like partial agonist


-low addiction/tolerance risk

Codeine

Opiate Receptor Agonist




-Antitussive action at does that don't produce analgesia

Loperamide

Opiate Receptor Agonist




-targets GI opiate receptors


-used as anti-diarrhea

Diphenoxylate

Opiate Receptor Agonist




-targets GI opiate receptors


-used as anti-diarrhea

Naloxone

Opiate Receptor Antagonist (used to initiate opiate withdrawal)




-IV only

Naltrexone

Opiate Receptor Antagonist (used to initiate opiate withdrawal)




-orally useful

Oxycodone + acetaminophen

aka Percocet




opiate receptor agonist combined with non steroidal anti-inflammatory drug

Hydrocodone + acetaminophen

aka Vicodin




opiate receptor agonist combined with non steroidal anti-inflammatory drug

Naloxone + Buprenorphine

Partiate opiate agonist, used to treat opiate addiction

Ziconotide

-non opiate


-Must be injected into the spine


-targets subunit of most types of neurnal Ca channel


-reduces transmitter release from many types of neuron


-reduces sensation of pain




Gabapentin

-non opiate


-Orally administered


-targets subunit of most types of neurnal Ca channel


-reduces transmitter release from many types of neuron


-reduces sensation of pain

Pregabalin

-non opiate


-Orally administered


-targets subunit of most types of neurnal Ca channel


-reduces transmitter release from many types of neuron


-reduces sensation of pain

Duloxetine

-non opiate


-5HT reuptake inhibitor


-usually used as an antidepressant

Imipramine

-non opiate


-5HT reuptake inhibitor


-usually used as an antidepressant

Fluoxetine

-non opiate


-5HT reuptake inhibitor


-usually used as an antidepressant