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10 Cards in this Set

  • Front
  • Back
what drugs are associated with an increased ANA?
1. procanimide
2. isoniazid
3. hydralazine
4. pheothazine
5. anti-TNF
1. how is RF detected?
2. what does CHRONIC stand for?
1. ELISA, agglutinatio
Ch: chronic disease
R: rheumatiod arthritis (80%)
O: other rheumatic dz (SLE, sjorgrens, MCTD, PSS, polymyositis
N:neoplasm
I: infection (AIDS, TB)
C: cyroglobinemia (esp HCV)
what do the following ANA patterns imply:
1. homogenous
2. rim
3. speckled
4. nucleolar
5. centromere
1. homo: SLE, drug
2. rim: SLE, A/I hepatitis
3. speck:SLE, MCTD, sjorgrens, SS
4. nuc:PSS
5. cent: CREST
is ANA a screening test?
no, 5% of normal population has ANA postive
3 causes for c-ANCA
Wegener’s
Microscopic PAN
Churg-Strauss
5 causes for p-ANCA
Microscopic PAN
Churg-Strauss
Pauci-immune GN
Drug induced syndromes
HIV
Autoimmune disease
what is normal ESR:
male
female
what causes it to vary?
1. male: age/2
2. female: age+10/2
3. varies with: age, gender, pregnancy, race, anemia, polycythemia
4 causes for high ESR (100mm/hr)
1. infection (bacteria)
2. connective tissue
3. malignancy
4. other
4 causes for low ESR (0mm/hr)
1. agammaglobulimemia
2. afibrinogenemia
3. extreme polycythemia
4. increased plasma viscosity
how is CRP measured?
immunoassay
*note it rises and falls faster than ESR