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10 Cards in this Set
- Front
- Back
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what drugs are associated with an increased ANA?
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1. procanimide
2. isoniazid 3. hydralazine 4. pheothazine 5. anti-TNF |
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1. how is RF detected?
2. what does CHRONIC stand for? |
1. ELISA, agglutinatio
Ch: chronic disease R: rheumatiod arthritis (80%) O: other rheumatic dz (SLE, sjorgrens, MCTD, PSS, polymyositis N:neoplasm I: infection (AIDS, TB) C: cyroglobinemia (esp HCV) |
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what do the following ANA patterns imply:
1. homogenous 2. rim 3. speckled 4. nucleolar 5. centromere |
1. homo: SLE, drug
2. rim: SLE, A/I hepatitis 3. speck:SLE, MCTD, sjorgrens, SS 4. nuc:PSS 5. cent: CREST |
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is ANA a screening test?
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no, 5% of normal population has ANA postive
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3 causes for c-ANCA
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Wegener’s
Microscopic PAN Churg-Strauss |
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5 causes for p-ANCA
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Microscopic PAN
Churg-Strauss Pauci-immune GN Drug induced syndromes HIV Autoimmune disease |
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what is normal ESR:
male female what causes it to vary? |
1. male: age/2
2. female: age+10/2 3. varies with: age, gender, pregnancy, race, anemia, polycythemia |
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4 causes for high ESR (100mm/hr)
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1. infection (bacteria)
2. connective tissue 3. malignancy 4. other |
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4 causes for low ESR (0mm/hr)
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1. agammaglobulimemia
2. afibrinogenemia 3. extreme polycythemia 4. increased plasma viscosity |
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how is CRP measured?
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immunoassay
*note it rises and falls faster than ESR |
