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8 Cards in this Set

  • Front
  • Back

Test color gm - vs gm +

Gm + is purple



Gm - is red

*Structure of Cell wall



+ chemical structure is crosslink of what?



What part of wall is good target for antibiotics

Outermost component of bacteria


Distinguish gm + from gm -


Contains peptidoglycan



Crosslink of sugar (glycan) and amino acids (peptide)



b 1-4, N-acetylglucosamine and N-acetylmuramic




Transpeptidases crosslink peptidoglycan, and inhibited by penicillin

*Difference in gm + and gm - cell wall?

Gm + is very thick wall, LTA, WTA, has MORE CROSSLINKING, susceptible to lysozyme




Gm - is thin wall, LPS, RESISTANT to lysozyme, less susceptible to antibiotics, has outer membrane with PORINS

LPS is in gm - or gm + only?



How resistant to antibiotics?



3 parts of structure?

Gm -



Resistant to antibiotics from hydrophobic permeability barrier



O antigen, Core, Lipid A

** Antigenic differences define serotypes.



Protects bacteria from phagocytosis***

Capsule

**Antigenic (H antigen) and recognized by Toll-like receptors



hint- Endows bacteria with motility

Flagella

**Mediate specific binding to host cells and other bacteria



Specific adhesin located at its top



hint- hair like structures



What type of this cell is involved in interactions between bacteria for genetic exchange?

Fimbriae (aka Pili)



F-pili (sex pili) involved in those interactions

**Resistant to heat, cold, drying, and chemicals



Formed in response to environmental stress



Vegetative state returns when nutrients return

Spores (Endospores)