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19 Cards in this Set
- Front
- Back
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what are 4 advantages of uric acid?
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anti-oxidant
blood pressure control in times of low salt ingestion intelligence neurodegenerative protective effects |
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what do most people have to prevent inflammatory response to ua?
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apo-E to coat
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what is the most common form of inflammatory arthritis in men older than 40?
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gout
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who will never have an acute gout attack and why?
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menstruating women because estrogen is protetive
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how can psoriasis predispose to gout?
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because it is rapidly proliferating cells that will excrete purines and uric acid
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what is stage I of classic gout?
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asymptomatic hyperuricemia
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what part of stage II gout has attacks lasting 1-2 weeks every 2-10 years?
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beginning
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what part of stage II gout has attacks lasting 1-3 weeks every 6 months to 2 years?
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middle
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what part of stage II gout has attacks lasting 1 week - 2 months every 2-3 weeks?
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late
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what is stage III of gout
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chronic arthritis with acute exacerbation
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what is classically the first attack of gout?
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podagra
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what prevents the immune response to uric acid?
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colchicine
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what crystalline disease is common in the elderly and due to impaired function of pyrophosphatases?
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calcium pyrophosphate deposition disease
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what disease should you suspect in elderly with inflammatory oligoarthritis?
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calcium pyrophosphate deposition disease
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what disease will result in rhomboid crystals?
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calcium pyrophosphate deposition disease
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what four joints are common in CPPD that differentiates it from gout?
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knee
shoulder wrist MCPs |
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is the onset of CPPD insideous or acute?
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insideous
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what are 4 associated medical conditions with CPPD?
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hypoerparathyroidism
hypothyroidism hemochromatosis hypomagnesmia |
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what can be used in severe cases of recurrent gout as a synthetic uricase?
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pegloticase
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