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23 Cards in this Set
- Front
- Back
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initial lab tests (6)
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hepatic and renal function
CBC w/ diff urinalysis CPK EKG Rheumatoid arthritis test |
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abnormal CXR will show
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most common = reticular
may also be nodular or mixed |
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complete PFTs include (3)
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spirometry (lung volumes)
diffusing capacity for CO resting/exercise pulse ox |
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when is a broncheoalveolar lavage performed?
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during fiberoptic bronchoscopy
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what does a bronchoalveolar lavage sample?
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cells and fluid from distal airways and alveoli
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what does a bronchoalveolar lavage check for? (3)
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cell count
cytology culture |
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when is a bronchoalveolar lavage required? (2)
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ILD + hemoptysis
helps locate the site of bleeding and evalutes the acute onset of ILD |
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scenarios requiring a lung biopsy (5)
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when no diagnosis from other facts can be made
atypical or progressive symptoms rapid deterioration if needed to exclude cancer or infection sudden change in radiographic features |
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mechanism of action
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injury
inflammation scarring |
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sarcoidosis symptoms (6)
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granulomas in the lung, lymph nodes, and skin
iritis, uneitis, cranial nerves, and salivary glands erythema noduosum hypercalcemia |
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sarcoidosis population
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women > men
african americans 20-40 |
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where is a biopsy of sarcoidosis best seen? (3)
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skin
liver eye |
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what unique test is helpful in sarcoidiosis
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angiotensin converting enzyme
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1-2-3 sign
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associated with sarcoidosis
frequently a separation between nodes and heart not usually seen in lymphoma |
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lofgren syndrome
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acute illness with bilateral hilar adenopathy, fever, erythema nodosum, and arthralgia
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drug induced ILD
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mostly reversible
often with eosinophilia in the blood may hear crackles, pleural rub PFTs reveal restrictive defect |
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most common offending agents in drug induced ILD (7)
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nitrodurantoin
methotrexate amiodarone bleomycin aspirin terbutaline talc |
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9 drug categories of drug induced ILD
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antibiotics
anti-inflammatory agents cardiovascular drugs antineoplastic agents CNS drugs oral hypoglycemic drugs illicit drugs oxygen radiation |
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difference between drug induced and radiation induced ILD
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radiation is localized to the size that is injured
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ILD associations with CT diseases (7)
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RA
SLE systemic sclerosis polymositis sjogren's syndrome mixed CT disorders ankylosing spondylitis |
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pulmonary vasculitis appearance on imaging
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non-ILD patterns
fleeting, evolving infiltrated cavitary lesions |
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loffler's syndrome
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transient or migratory pulmonary infiltraes with blood eosinophilia
caused by parasitic infections and acute hypersensitivity to drugs |
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bronchiolitis obliterans
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intraluminal polyploid plug of granulation tissue in terminal and respiratory bronchioles resulting in ILD, COPD appearance
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