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23 Cards in this Set

  • Front
  • Back
Two drug classes used to increase HR for a bradyarrhythmia:
-Anticholinergics
(Atropine, Glycopyrolate)

-Sympathomimetics
(Terbuteline, Theophyline, Isoproterenol)
Three drug classes used to decrease HR for a supraventricular tachyarrhythmia:
-Beta blockers (Atenolol, Sotalol)

-Calcium channel blockers (Diltiazem, Amlodipine)

-Digoxin
The difference on effect of heart contractility between the three drug classes used for supraventricular tachyarrhythmia:
Beta blockers, calcium channel blockers: (-) inotropes

Digoxin: (+) inotrope
Two IV ventricular antiarrhythmics:
-Lidocaine
-Procainamide
The two safest oral antiarrhythmics:
-Sotalol
-Mexelitine
Common side effect of all ventricular antiarrhythmics:
Pro-arrythmic effects
Contraindication of all ventricular antiarrhythmics:
Presence of ventricular escape beats
Difference between an anticoagulant and a thrombolytic:
-Anticoagulant: impact ability of blood to clot

-Thrombolytic: used to try to break down a blood clot once it has already formed
An anticoagulant that can be given IV for emergency situations:
Heparin
Two anticoagulants that can be given orally:
-Aspirin
-Clopidogrel
Most common indication for an anticoagulant in a cat:
Atrial enlargement observed with feline cardiomyopathy
Most potent diuretic used in veterinary medicine:
Furosemide (Lasix)
Explain the RAAS system effects of Spironolactone and their effect on survival in heart failure:
Spironolactone blocks aldosterone at the level of the collecting duct (and decreases sodium conduction at the Na/K/ATPase pump, "sparing potassium"). Blocking aldosterone increases survival time.
Two common neutroceuticals:
-Taurine
-L-carnitine
The indication for free fatty acids:
Congestive heart failure
Define the impact of a positive inotrope on contractility:
Positively increases contractility (increased contraction)
Define the impact of a negative inotrope on contractility:
Negatively increases contractility (decreased contraction)
The strongest and safest oral positive inotrope for veterinary practice:
Pimobendan
Three positive benefits of Pimobendan for canine heart failure:
-Positive inotrope
-Vasodilator
-Increased length of survival
Two indications for vasodilators:
-Systemic hypertension
-Congestive heart failure (to decrease preload or afterload)
Three types of vasodilators and one type of each:
-Arterial (afterload reducers): Hydralazine, Amlodipine

-Venous (preload reducers): Nitroglycerin

-Mixed/balanced (arteries and veins): ACE inhibitors (Enalapril, other -prils)
Name the group of vasodilators that increase life span in CHF and be able to explain the mechanism that makes them beneficial:
ACE inhibitors

Help regulate the RAAS in heart failure by preventing action of Angiotensin Converting Enzyme and conversion of ANG I --> ANG II (and subsequent vasoconstriction, increased sympathetic tone, myocardial remodeling, etc.)
Therapeutic monitoring to be implemented with ACE inhibitor therapy:
Must monitor renal parameters and electrolytes