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11 Cards in this Set
- Front
- Back
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Celiac Disease
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- T cell mediated immune response in the proximal small intestine to gluten
- must have the D2 or D8 human leukocyte antigen (HLA) |
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Inflammatory response in Celiac Disease
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- gluten peptides (gliadin) initiate immune response from the cells lining the intesting
- cells produce TNF-a and IFN-y --> release of chemokines and chemotactic factors - produce IgA antigliadin antibodies - chronic inflammation destroys the intestinal villi |
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Describe the clinical presentation of celiac disease
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- classic malabsorptive symptoms
- weight loss, diarrhea or steatorhea and failure to thrive with nutrient deficiencies - Fe deficiency anemia, wt loss or diarrhea - abdominal pain and bloating, gas production, abdominal cramps - anemia - iron, B12 or folate - higher risk for lymphoma and osteoporosis |
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Health Canada has approved the ______ to diagnose celiac disease
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Biocard Celiac Test Kit
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Goal of treatment of celiac disease
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relieve symptoms, heal the intestine, reverse consequences of malabsorption
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Health Canada's Position on oats and celiac disease
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- 50 - 70 grams/day of pure oats can be tolerated as recommended by the Canadian Celiac Association
- uncontaminated pure oats (<20ppm gluten) - oats should only be introduced when pt is symptom free and stable on the GF diet |
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Nutritional Therapy for CD - Assessment
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wt history
diet history supplementation details on malabsorption, GI symptoms any nutrient deficiencies |
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Counseling topics for CD
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- need for strict adherence
- sources of gluten |
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Food Additives to Avoid - CD
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- Malt/malt flavouring/malt syrup
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Objective: Living with celiac disease and gluten-free diet - a canadian perspective - Zarkadas, 2013
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The purpose of this cross-sectional study was to evaluate the difficulties experienced, the strategies used and the emotional impact of following a gluten-free diet among Canadians with celiac disease
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Results: Living with celiac disease and gluten-free diet - a canadian perspective - Zarkadas, 2013
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Difficulties and negative emotions were experienced less frequently by those on the diet for >5 years, although food labelling and eating away from home remained very problematic. Frustration and isolation because of the diet were the most common negative emotions experienced.
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