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28 Cards in this Set
- Front
- Back
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What is the role of the liver? |
metabolism, digestion,detoxification, elimination of substances from the body |
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What is the functional unit of the liver? |
lobules |
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What are the small spaces betweenhepatocytes that form intrahepatic ducts where excretory products of cell candrain? |
Bile canaliculi |
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Yellow discoloration ofskin, eyes (sclera), and mucous membranes is referred to as: |
Jaundice |
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Hepatic jaundice is caused by: |
disorders of bilirubin metabolism and transport defects |
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The presence of scar tissue in the liver is called |
cirrhosis |
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Reyes syndrome is associated with: |
children who are administered aspirin during a viral syndrome |
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Bilirubin is a waste product of _________ catabolism. |
heme |
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Bilirubin is measured using which methods? |
Jendrassik-Grof (caffeine-benzoate) or Malloy Evelynmethods |
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Bilirubin testing utilizes a _____________ reaction. |
diazo |
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Samples to be tested for bilirubin must be: |
protected from light |
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Bilirubin in a sample would produce a ______________ color and is referred to as ______________. |
green/yellow; icteric |
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Conjugated (direct) bilirubin is bound to: |
glucuronic acid |
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Which enzyme catalyzes the conjugation of bilirubin? |
UDP-glucuronyltransferase |
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Unconjugated (indirect) bilirubin hangs on to: |
albumin to be transported |
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_______________ bilirubin is lipid soluble. |
Unconjugated |
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_______________ bilirubin is water soluble. |
Conjugated |
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High levels of unconjugated bilirubin accumulated in the brain is known as: |
kernicterus |
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The colorless end product ofbilirubin metabolism that is oxidized by intestinal bacteria to brown pigment |
urobilinogen |
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Absence of urobilin from urine and stool is seen with: |
complete biliaryobstruction (cholestasis) |
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Testing for urobilinogen utilizes ______________ reagent |
Ehrlich's |
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Which enzymes can be tested for obstructive disorders? |
Gamma-glutamyltransferase and Alkaline phosphatase |
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Hepatitis A is transmitted via the ________________ route. |
oral-fecal |
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The most common form of viral hepatitis worldwide is: |
Hepatitis A |
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Hepatitis ______ is a DNA virus |
B |
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Which hepatitis B marker is detectable the first 3-5 weeks after infection? |
HBsAg |
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Which type of hepatitis can lead to liver cancer? |
hepatitis C |
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Which type of hepatitis causes serious issues in pregnant women and is often spread in waterborne epidemics? |
Hepatitis E |
