Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
35 Cards in this Set
- Front
- Back
|
What is the MoA of pyrethrins?
|
Inhibit GABA binding
|
|
|
What is the MoA of organophosphates/ carbamates?
|
Inhibit Ach breakdown (acetylcholinesterase inhibition)
|
|
|
What is the MoA of Fipronil?
|
Inhibit GABA binding
|
|
|
What is the MoA of Imidacloprid?
|
Bind to AchR - paralysis
|
|
|
What is the MoA of Lufenuron?
|
Inhibit chitin
|
|
|
What is the MoA of Nitenpyram?
|
Bind to AchR - paralysis
|
|
|
What animal is contraindicated for pyrethrin use?
|
Cats
|
|
|
What animals are contraindicated for organophosphates?
|
Cats, Greyhounds, Whippets, Charolais, Gelbvich, Simmental, Brahman cattle
|
|
|
What are three drug contraindications for organophosphates?
|
1. NMJ drugs
2. CP450 drugs 3. Cholinergic drugs |
|
|
Which of the following drugs are contraindicated in nursing, pregnant or debilitated animals?
a. K9 Advantix - imidacloprid + permethrin b. Frontline - Fipronil c. Advantage - Imidacloprid d. Program - Lufenuron e. Capstar - Nitenpyram |
K9 Advantix - imidacloprid + permethrin
Advantage - imidacloprid |
|
|
What is the difference in Sentinel (Milbemycin oxime/Lufenuron) and Interceptor (Milbemycine oxime)?
|
Sentinel is for dogs only
Interceptor is for both dogs and cats |
|
|
What can Milbemycin oxime (Interceptor) do that Fipronil (Frontline) and Imidacloprid + permethrin (K9 Advantix) cannot?
|
Heartworm preventative, control/remove round and whipworms, hookworms
|
|
|
What can Selamectin (Revolution) do that Fipronil (Frontline) cannot?
|
Heartworm preventative - kills microfilaria
|
|
|
What is the MoA of Benzimidazoles?
|
Bind to tubulin - inhibit egg production
|
|
|
What is the MoA of Pyrantal (Strongid)?
|
Cholinergic AGONIST - spastic paralysis
|
|
|
What is the MoA of Piperazine?
|
GABA agonist
|
|
|
What is the MoA of Avermectins and milbemycins?
|
Increase GABA release - flaccid paralysis
|
|
|
What is the MoA of Praziquantel?
|
Vacuolization of integument
|
|
|
What is Levamisole used for? What animal is contraindicated for its use?
|
Nematodes only
Not used in horses |
|
|
What are the Benzimidazoles used for?
|
Nematodes, some Cestodes, Giardia
|
|
|
What is the safest and broadest spectrum Benzimidazole?
|
Fenbendazole
|
|
|
What Benzimidazole is most effective against small strongyles?
|
Oxibendazole
|
|
|
What is the most systemically absorbed Benzamidazole?
|
Albendazole
|
|
|
What can Albendazole kill that Fenbendazole cannot?
|
Trematodes
|
|
|
What animal is Albendazole contraindicated for? Why?
|
GI and BM toxicity in camelids and small animals
|
|
|
What is Piperazine used for? What drug cannot be used at the same time?
|
Nematodes - roundworms only
Cannot be used at the same time as Pyrantel Piperazine - flaccid paralysis Pyrantel - spasmodic paralysis |
|
|
What equine dewormer cannot be used in foals < 4 months of age? Why?
|
Moxidectin
Neurotoxicity |
|
|
What do Macrolide endectocides (Avermectin, milbemycins) kill?
|
Nematodes, arthropods
NOT cestodes or trematodes |
|
|
What do Isoquinolones like Praziquantel kill?
|
Cestodes and Trematodes
|
|
|
What animals are approved for Levamisole use?
|
Cattle, pigs, sheep
|
|
|
What animals are approved for Fenbendazole?
|
Everyone! - Dogs, cattle, sheep, horses, cats, young, preg, debilatated.
Minimal GI absorbance |
|
|
What animals are approved for Albendazole?
|
Cattle
|
|
|
What animals are approved for Pyrantal?
|
Everyone
|
|
|
What does Pyrantal (Strongid) kill?
|
Nematodes (except whipworms)
Cestodes in horses when 2x dose is used |
|
|
What does Piperazine kill? In what species is toxicity increase because of systemic absorption?
|
Nematodes - roundworms only = NARROW SPECTRUM
Cats |
