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17 Cards in this Set

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What is the incidence of CL/CLP in whites?
1 in 750
What is the incidence of CL/CLP in asian?
1 in 500
What is the incidence of CL/CLP in black?
1 in 2000
What is the ratio of left to right to bilateral clefts
6:3:1
what is the ratio of CLP to CL?
2:1
What is the risk of having a child with CLP if the parents have 1 child with CLP?
4%
What is the risk of having a child with CLP if one parent has CLP?
2% to 4%
What is the risk of having a child with CLP if the parents have 2 child with CLP?
9%
What is the risk of having a child with CLP if one child and one parent have CLP?
14% to 17%
What is the normal vertical length of the upper lip in a newborn, age 3 months, and adult?
10mm,13mm, 17mm
What syndromes are associated with CLP/CL?
Van der woude, waardendurg' syndrome, down syndrome, trisomy 13, stickler's syndrome, Pierre Robin sequence, velocardiofacial syndrome and median cleft lip
What is the inheritance pattern of Van der Woude's syndrome?
Autosomal Dominant
What are the associated findings in Van der Woude's syndrome?
lip pits, absent second molars, syndactyly, adnormal genitalia, and popliteal pterygia
What is the cause of waardenburg syndrome?
abnormal development and migration of neural crest cells
What is the inhertiance pattern of Stickler's syndrome?
Autosomal dominant
What are the typical features of Stickler's syndrome?
CP, progressive joint degeneration, ocular abnormalities leading to blindness
what is the rule of tens?
10 weeks, weight 10 pounds, and have a hemoglobin of at least 10 mg/dl