Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
38 Cards in this Set
- Front
- Back
|
Methacholin
|
- Direct agonist
- cholinomimetric - beta methyl group |
|
|
Carbachol
|
- Direct agonist
- carbamoyl group - resistant to cholinesterase |
|
|
Bethanechol
|
- Direct agonist
- carbamoyl group + beta methyl - only oral cholinester used = postoperative ileus, bladder atony |
|
|
Pilocarpine
|
- direct agonist
- alkaloid used = glaucoma |
|
|
Nicotine
|
- direct agonist
- alkaloid |
|
|
Cevimeline
|
- Agonist
- M3 selectivity used = dry mouth of Sjogren's syndrome |
|
|
Physostigmine
|
- Indirect Agonist
- AChEI used = Antimuscarinic drug intoxication |
|
|
Edrophonium
|
- Indirect Agonist
- AChEI |
|
|
Neostigmine
|
- Indirect Agonist
- AChEI used = Postoperative ileus, bladder atony, Myasthenia gravis |
|
|
Rivastigmine
|
- Indirect Agonist
- AChEI used = Alzheimer's |
|
|
Donepezil
|
- Indirect Agonist
- AChEI used = Alzheimer's |
|
|
Varenicline
|
- Partial Agonist
- Chantix used = smoking cessation |
|
|
Demecarium
|
- Indirect Agonist
- long lasting AChEI used = Glaucoma |
|
|
Echothiophate
|
- Indirect Agonist
- long lasting AChEI used = Glaucoma |
|
|
Galantamine
|
- Indirect Agonist
- AChEI used = Alzheimer's |
|
|
Tacrine
|
- Indirect Agonist
- AChEI used = Alzheimer's |
|
|
Pyridostigmine
|
- Indirect Agonist
- AChEI used = Myasthenia gravis |
|
|
Lobeline
|
- Direct Agonist
- alkaloid |
|
|
Atropine
|
- Nonselective Antagonist
used = mydriasis, vasovagal attack, muscarinic poisoning, decrease salivation/secretions during surery |
|
|
Pirenzepine
|
- Antagonist
- selective M1 blocker used = treat peptic ulcer by decreasing gastric acid secretion |
|
|
Telenzepine
|
- Antagonist
used = reduce gastric acid secretion |
|
|
Dicyclomine
|
- Antagonist
used = irritable bowel syndrome |
|
|
Trihexyphenidyl
|
- Antagonist
used = Parkinson's disease |
|
|
Darifenacin
|
- Antagonist
- M3 selective used = overactive bladder |
|
|
Solifenacin
|
- Antagonist
- M3 selective used = overactive bladder |
|
|
Oxybutynin
|
- Antagonist
- M3 selective used = overactive bladder |
|
|
Tolterodine
|
- Antagonist
- M3 selective used = overactive bladder |
|
|
Scopolamine
|
- Antagonist
- cross BBB used = Motion sickness |
|
|
Methscopolamine
|
- Antagonist
- quat ammonium, low CNS penetration used = GI hypermotility and secretion (diarrhea and cramps) |
|
|
Glycopyrrolate
|
- Antagonist
- quat ammonium, low CNS penetration used = GI hypermotility and secretion (diarrhea and cramps) |
|
|
Ipratropium
|
- Antagonist
- quat ammonium - produces bronchodilation used = COPD and asthma |
|
|
Tiotropium
|
- Antagonist
- quat ammonium - produces bronchodilation used = COPD and asthma |
|
|
Pirenzepine
|
- Antagonist
- M1 selective used = treat peptic ulcer |
|
|
Succinylcholine
|
- Antagonist
- depolarizing blocker (prototype) - only desensitization blocker on the market used = induce muscle relaxation |
|
|
Pancuronium
|
- Antagonist
- nondepolarizing blocker used = induce muscle relaxation |
|
|
Rocuronium
|
- Antagonist
- nondepolarizing blocker - most rapid used = induce muscle relaxation |
|
|
Diphenoxylate
|
- Antagonist
used = treat Diarrhea |
|
|
Tubocurarine
|
- Antagonist
- nondepolarizing blocker (prototype) used = induce paralysis |
