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17 Cards in this Set
- Front
- Back
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What are the direct-acting cholinergic agonists?
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- Acetylcholine
- Bethanechol - Carbachol - Pilocarpine |
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What are the reversible anticholinesterases?
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- Physostigmine
- Neostigmine - Pyridostigmine - Edrophonium |
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What are the irreversible anticholinesterases?
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- Isoflurophate
- Echothiophate |
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What are the general actions of cholinergic agonists?
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- decreased HR, CO, and BP
- increased salivation and sweating - miosis - increased GI motility - increased bronchial secretions - increased accommodation - bladder stimulation |
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What are the adverse effects of cholinergic agonists?
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- sweating and flushing
- salivation - hypotension - nausea - abdominal pain and diarrhea - bronchospasm - urinary incontinence |
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Which direct-acting cholinergic agonists stimulate both nicotinic and muscarinic receptors?
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- Acetylcholine
- Carbachol |
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Which direct-acting cholinergic agonists only stimulate muscarinic receptors?
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Bethanechol and Pilocarpine
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Which direct-acting cholinergic agonist is used in emergency lowering of IOP?
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Pilocarpine
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Which reversible anticholinesterase can be used in an atropine overdose?
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Physostigmine
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Which reversible anticholinesterase can be used in the chronic treatment of myasthenia gravis?
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Pyridostigmine
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Which reversible anticholinesterase can be used to DIAGNOSE myasthenia gravis?
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Edrophonium
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Which irreversible anticholinesterase can be used in the chronic treatment of POAG?
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Isoflurophate
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Which irreversible anticholinesterase can be used in the managament of accommodative esotropia?
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Echothiophate
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What is a potential side effect of Echothiophate?
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Iris cysts.
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Pralidoxime can be used to reactivate ________________.
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acetylcholinesterase
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Besides the treatment of accomodative esotropia, echothiophate can also be used for what purpose?
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to break synechiae
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When are strong miotics, such as pilocarpine or echothiophate, contraindicated?
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high myopes (due to risk of retinal detachment)
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