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14 Cards in this Set
- Front
- Back
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Taxonomic classification? (5)
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Kingdom - Bacteria
Class - Chlamydiae Order - Chlamydiales Family - Chlamydiaceae Genus - Chlamydia |
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Chlamydia characteristics? (4)
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1. GN obligate intracellular bacteria
2. LPS (+); muramic acid (-) = no PG layer 3. No ATP syn (=ATP parasite) 4. Biphasic reproductive cycle |
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Chlamydia spp? (3)
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1. Chlamydia trachomatis
2. Chlamydophila pneumoniae 3. Chlamydophila psittaci |
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Comparison of EB vs. RB?
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3 biotypes: C. trachomatis? (3)
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1. MoPn (pneumonia in mice)
2. TRIC (Trachoma-Inclusion conjuctivitis) 3. LGV (lymphogranuloma venereum) |
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C. trachomatis serotypes: A, B, Ba, C?
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1. TRIC biotype
2. *trachoma --> *blindness |
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C. trachomatis serotypes: D-K? (4)
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1. TRIC biotype
2. *eye and genital infections 3. *pneumonia newborns 4. *NGU (non-gonorrhoeal urethritis) |
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C. trachomatis serotypes: L1-L3? (2)
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1. LGV biotype
2. *severe genital veneral disease |
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C. trachomatis: THERAPY? (2)
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1. Tetracyclines
2. Macrolides (i.e. azithromycin) |
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C. trachomatis: DIAGNOSIS? (6)
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1. Clinical specimen --> transport media
2. Culture (cell lines, embryonated eggs) 3. Serology (AG identification - MOMPs, LPS) 4. ELISA, direct IF (direct AG detection) 5. PCR (chlamydial DNA detection) 6. Giemsa stain (detects EB/inclusion bodies) |
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Chlamydophila pneumoniae? (3)
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1. upper+lower resp. tract infection (i.e. pharyngitis, laryngitis)
2. Atypical pneumonia (?) 3. Target cells: macrophages, lung parenchyma |
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Chlamydophila psittaci? (4)
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1. Carriers - birds in RI, stool
2. Infection - aerosol 3. *psittachosis --> *flu-like symptoms (pneumonia, meningoencephalitis, peri/myocarditis) 4. Target cells: macrophages, lung parenchyma |
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Chlamydophila psittaci: THERAPY? (2)
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1. Tetracyclines
2. Erythromycin (macrolide) |
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Chlamydophila pneumoniae: THERAPY? (3)
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1. Macrolides
2. Tetracyclines 3. Fluoroquinolones |
