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15 Cards in this Set
- Front
- Back
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loop diuretics
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1. NKCC in TAL
2. dont use NSAIDs or digitalis (hypokalemia) 3. decrease preload and decreas afterload 4. doesnt increase longevity |
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thiazide diuretics
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1. Na/Cl in DCT
2. decrease preload and decrease TPR 3. doesnt increase survival 4. hypokalemia (dont use with digitalis) |
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K sparing diuretic
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1. remodal heart
2. increase survival |
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ACEi
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1. -oprils
2. DOC CHF 3. remodel and increase survival 4. decrease afterload and decrease preload indirectly 5. bradykinin cough, escape phenomenom |
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ARB
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1. -artans
2. block AT1 causing vasodilation and remodeling 3. decrease preload and decrease afterload |
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Sodium Nitroprusside
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1. acute
2. IV only 3. converted NO 4. decrease preload and afterload |
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Nitroglycerin
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1. acute tx of chronic angina
2. decrease preload and some afterload effect 3. sublingual DOC for angina |
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Hydralazine/minoxidil
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1. decrease afterload
2. othostatic hypotension 3. chronic tx |
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isosorbide dinitrite
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1. converted to NO
2. decrease preload and increase renal Q 3. orthostatic hypotension 4. chronic tx |
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bidil
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1. isosorbid dinitrite + hydralazine
2. for those who cant take ACEi or ARB 3. increases survival |
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cardiac glycoside
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1. digoxin t1/2 < digitoxin t1/2
2. digoxin cleared kidney, digitoxin by liver 3. increased FC and increased renal Q 4. yellow vision 5. C/I hypokalemia, BB, and CCB doesnt increase survival |
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Dopamine
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1. D1, B1, alpha 2 agonist
2. low levels = increased renal Q 3. use acutely |
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Dobutamine
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1. primarily B1 agonist
2. use acutely 3. high dose will increase chronotropy |
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PDEi
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1. inamrinone, milrinone
2. increase FC 3. same effect caffeine/glucagon 4. BB OD |
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Beta Blocker
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1. G1 bisprolol (B1B2), G2 metoprolol (B1), G3 carvedilol (B1B2a1)
2. beta arrestin 3. only drug increase EF 4. increases longevity 5. get worse b/f get better 6. not for decompensated HF |
