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6 Cards in this Set
- Front
- Back
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what is a common target for chemo?
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cell growth - relative selective toxicity
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what is tumor cell burden/tumor load?
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mass of tumor and the heterogenicity of the cells in the tumor
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who do you use combination of drugs to treat cancer?
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1. combat resistance development
2. increase spectrum |
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who do you want to treat cancer early?
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growth rates eventually = normal cell growth rate
- become kinetically more resistant with time |
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what is kinetic resistance?
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increasing difficulty in drugs to reach target as the tumor grows
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what is the primary deter of cell's kinetic sensitivity?
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where they are in the cell cycle
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