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27 Cards in this Set

  • Front
  • Back

Chromosome

A rodlike structure in the cell nucleus, along which the genes are located; it is composed of DNA surrounded by other material, mainly proteins

Polymer

A substance composed of a large number of atoms; these atoms are usually arranged in repeating units, or monomers

Nucleotide

The unit of DNA consisting of one of four bases - adenine, guanine, cytosine, or thymine- attached to a phosphate-sugar group

Complementary Base Pairing

The specific pairing of base A with T and base C with G in double-stranded DNA

Proteins

Polymers of amino acids that play basic roles in the structures and functions of living things

Amino Acids

The building blocks of proteins; there are twenty common amino acids; amino acids are linked to form a protein; the types of amino acids and the order in which tehy're linked determine the character of each protein

Human Genome

The total DNA content found within the nucleus of a human cell; it is composed of approximately three billion base pairs of genetic information

Replication

The synthesis of new DNA from existing DNA

Polymerase Chain Reaction (PCR)

A technique for replicating or copying a portion of a DNA strand outside a living cell; this technique leads to millions of copies of a DNA strand

Primer

A short strand of DNA used to target a region of DNA for replication by PCR

Hybridization

The process of joining two complementary strands of DNA to form a double-stranded molecule.

Tandem Repeat

A region of a chromosome that contains multiple copies of a core DNA sequence that are arranged in a repeating fashion.

Restriction Fragment Length Polymorphisms


(RFLPs)

Different fragment lengths of base pairs that result from cutting a DAN molecule with restriction enzymes

Short Tandem Repeat


(STR)

A region of a DNA molecule that contains short segments consisting of three to seven repeating base pairs

Electrophoresis

A technique for separating molecules trough their migration on a support medium while under the influence of an electrical potential

Multiplexing

A technique that simultaneously detects more than one DNA marker in a single analysis

Amelogenin Gene

A genetic locus useful for determining gender

Y-STRs

Short tandem repeats located on the human Y chromosome

Mitochondria

Small structures located outside the nucleus of a cell; these structures supply energy to the cell; maternally inherited DNA is found in each mitochondria

Picogram

One-trillionth of a gram, or .000000000001 gram

Low Copy Number

Fewer than 18 DNA-bearing cells

Epithelial Cells

The outer layer of skin cells; these DNA-bearing cells often fall off or are rubbed off onto objects retrieved from crime scenes

Touch DNA

DNA from skin cells transferred onto the surface of an object by simple contact

Substrate Control

An unstained object adjacent to an area on which biological material has been deposited

Buccal Cells

Cells derived from the inner cheek lining

Sequencing

A procedure used to determine the order of the base pairs that constitute DNA

Deoxyribonucleic Acid


(DNA)

The molecules carrying the body's genetic information; double stranded in the shape of a double helix