Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
49 Cards in this Set
- Front
- Back
|
Individuals who are LE (a-b-) and can develop Lewis antibodies w/o exposure to Lewis antigens are called
a) immune mediate b) biphasic c) natural occuring d) autoantibodies |
naturally occuring
|
|
|
At what phase of the antihuman globulin test will any Fya or anti Fyb be detected?
a) IS b) 37 c) AHG d) all of above |
AHG
|
|
|
A blood bank technologist needed to confirm the presence of anit p1 in a patient specimen. Fresh cells were not available so an old panel that contained cells positive of p1 was used. No cells positive for the antigen reacted at any phase of the antiglobulin test wheareas cells from the screening cells show specificity for the presence of anti P1. What is the possible explanation
|
P1 deteriorates rapidly upon storage
|
|
|
Anti Lu1 reacts at what temperature?
a) room temp b) 37 b) AHG c)all of above d) |
room temp
|
|
|
What is the definition of blood group system?
|
a group of antigens produced by alleles at a single gene locus
|
|
|
Lewis antibodies are of what immunoglobulin class?
a) IGM b) IgG c) IgA d) IgE |
IGM
|
|
|
What sequence of antigens coinsides with stongest immnogen to weakest immunogen
a) D, Fya, Fyb, K b) D, K , Fya, Fyb c)Fya, Fyb, D, K d K, Fya, Fyb, D |
b) D, K, Fya, Fyb
|
|
|
What fatal disease is associated with the McLeod phenotypes?
|
Chronic granulomatous disease
|
|
|
Why is the Le System not implicated in hemolytic disease of the newborn (HDN)?
|
Lewis antigens are not well developed at birth
|
|
|
Which population has the greatest frequency of the Fy (a-b-) phenotype
|
Black
|
|
|
The S and s antigens are found in which glycoprotein?
|
glycoprotein B
|
|
|
The S and s antigens are found in which glycoprotein?
|
glycoprotein B
|
|
|
The M and n antigens are found in which glycoprotein
|
glycoprotein A
|
|
|
The M and n antigens are found in which glycoprotein
|
glycoprotein A
|
|
|
codominent antigens
|
M+N+ weaker
M+N- stronger |
|
|
codominent antigens
|
M+N+ weaker
M+N- stronger |
|
|
Which antigens show dosage?
|
Duffy
MNS Kidd |
|
|
Which antigens show dosage?
|
Duffy
MNS Kidd |
|
|
Compatibility tests phases are?
|
IS, 37, AHG
|
|
|
Compatibility tests phases are?
|
IS, 37, AHG
|
|
|
Serologic tests determine a persons
|
phenotypes
|
|
|
Serologic tests determine a persons
|
phenotypes
|
|
|
All of the following are characteristic of Kidd antibody except
a) IgG b) ability to bind compliment c) naturally occuring d)exhibit dosage |
naturally occuring
|
|
|
All of the following are characteristic of Kidd antibody except
a) IgG b) ability to bind compliment c) naturally occuring d)exhibit dosage |
naturally occuring
|
|
|
The kell gene is located on the long arm of which chromosome?
a) 7 b) 5 c) 9 d) 11 |
a) 7
|
|
|
The kell gene is located on the long arm of which chromosome?
a) 7 b) 5 c) 9 d) 11 |
a) 7
|
|
|
Duffy gene is located in what chromosome
a)6 b)3 c)19 d)1 |
d) 1
|
|
|
Duffy gene is located in what chromosome
a)6 b)3 c)19 d)1 |
d) 1
|
|
|
Xg is sex linked what is Xga+ and Xga- and thier frequencies
|
Xga+ female 89%
Xga- male 66% |
|
|
Xg is sex linked what is Xga+ and Xga- and thier frequencies
|
Xga+ female 89%
Xga- male 66% |
|
|
What race does Diego show up most in?
|
Mongolian
South Americans |
|
|
Antithetical
|
codominant
|
|
|
What is LISS
|
enhancement agent
|
|
|
what is rule of three
|
three negatives
three positive |
|
|
All of the following are characteristic of Kidd Antibodies except
a)IgG b)ability to bind compliment c)natural occuring d)exhibit dosage |
naturally occuring
|
|
|
The kell gene is located of the long arm of which chromosome?
a) 5 b) 7 c) 9 d) 11 |
b) 7
|
|
|
The kidd gene is located in which chromosome?
a)18 b)3 c)19 d)1 |
a) 18
|
|
|
what abnormal blood cell morphology is associated with the McLeod phenotype?
a)sperocytes b)ovalacytes c)sickle cells d)acanthocytes |
d) acanthocytes
|
|
|
The M and N antigens exhibit dosage. Therefore, if a person inherits a homozygous genotypes their red blood cell will react ______with anti M than a person with a heterozygous genotypes of MN
|
Stronger
|
|
|
What type of hemolytic transfusion reaction occurs more frequently in patients with JK antibodies
a)febrile b)delayed c)immediate d)bacterial |
Jk is Kid delayed
|
|
|
Most blood group alleles are
a)x linked dominant b)x linked recessive c)codominant d)none of above |
codominant
|
|
|
Molecular testing test for
|
genotype
|
|
|
Alloantibodies
|
same species
found in transfusions |
|
|
Autoantibodies
|
self
|
|
|
When do babies get all of the antibodies
|
6 months
|
|
|
Chronic Granulocytosis
CGD (Kell) |
white cells not functioning
something is missing cannot produce H202 will not kill bacteria |
|
|
Proteolytic enzymes
|
Bromolin fician papain
|
|
|
What is the function of LISS
|
breaks the reaction
A type of potentiating medium in use for serological testing. Reducing the ionic strength of red blood cell suspending medium increases the affinity of the antigen for its corresponding antibody |
|
|
What is in the screeniing cells
|
Group O
|
