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61 Cards in this Set

  • Front
  • Back

mental activity

mentation

short-term memory and learning ability

Examples of cognitive functions

-is a sudden, transient state of confusion.

delirium


Comparison of Dementia and Delirium


Onset


Dementia -gradual


delirium--Sudden


Comparison of dementia and delirium


presentation


dementia--alert, attentive


delirium--blunted inattentive


dementia vs delirium


course


dementia--stable, progressive deterioration, extended


delirium--unstable, fluctuations in function, brief


dementia vs delirium


duration


dementia--permanent


delirium-temporary


dementia vs delirium


treatment


dementia--symptomatic or supportive


delirium--temporary specific


dementia vs delirium


outcome


dementia--incurable


delirium--curable


dementia vs delirium


__can result from high fever, head trauma, brain tumor, drug intoxication or withdrawal disorders, or inflammatory disorders of the CNS.

delirium

__is more commonly in older adults, refers to conditions in which decline in memory, thinking, and reasoning is severe enough to affect daily life of an alert person.

dementia

__the most common cause of dementia, is a progressive, deteriorating brain disorder.

Alzheimer's disease

What are the two types of Alzheimer's Disease?


early onset (btwn 30-60 yrs old)


late onset (after 60)


Alzheimer's Disease


Early onset is believed to be caused by what?

A mutated gene within specific chromosomes (1,14,21) that are responsible for making proteins that promote survival of nerve cells.

The mutated genes in Early onset Alzheimer's are cause a disruption in the processing of a substance known as __

amyloid precursor protein (APP)


T or F


Having a first degree relative with Ad in late onset doubles the risk for acquiring the disease.


False


Having a first degree relative in early-onset doubles your chances

What causes AD in late-onset

the etiology of late-onset is unclear, but a combination of genetic, environmental, and lifestyle factors may be a factor


Late - onset AD


One risk factor for Ad is attributed to __, one of a pair of genes, occupying chromosome 19 that regulates the formation of apolipoprotein.

allele

The onset of Ad is __and symptoms may develop slowly over years.

insidious

What are the stages of AD?


preclinical


mild cognitive impairment


Alzheimer's dementia

What happens during the preclinical stage?

a period when amyloid plaques are accumulating and nerve cell changes are occurring, but there are no clinical symptoms of AD

What happens during the mild cognitive impairment stage?

a time when memory problems are noticed but not serious enough to interfere with independent living

What happens during the Alzheimer's dementia stage?

the point at which there is significant cognitive decline, such as difficulty recalling words, trouble learning new information, difficulty recognizing familiar faces, impaired reasoning, judgment, and problem solving.

What is the classic sign for AD?

memory loss-it's confined at first to recent information and eventually long-term memory becomes impaired.

aphasia

problems with speaking

alexia

problems with reading

agraphia

problems with writing

acalculia

problems with calculating

ataxia

difficulty walking

apraxia

inability to accomplish ADLs

biomarkers

a measurable indicator of some biological state



How does a patient get a diagnosed of AD?
AD diagnosis currently relies on validating mental decline and by excluding other causes for client's symptoms
What is the AD7C test?


Test developed by Nymox Pharmaceutical




Uses human urine or cerebrospinal fluid to detect the presence of beta amyloid ad tau proteins.

How can the early onset familial type of AD be identified?
Genetic testing to identify the defective trait
What test can help identify the late onset of AD?

Blood test that can identify APOE 4

T or F




There is a cure for AD.


False




There is no cure for AD; treatment is supportive using on of various drugs currently available



Until recently, AD could only be confirmed ___

during a postmortem examination


Diagnosing AD




__scan shows shrink of the cerebral cortex, but this wouldn't be apparent during the early stages.


Computed Tomography (CT)

Diagnosing AD




__and __ provide structural and metabolic information about the brain.


Positron emission tomography (PET) and magnetic resonance imaging (MRI)

Diagnosing AD




__detects slower-than-normal brain waves.


Electroencephalography



Current drugs approved for the treatment of dementia of Alzheimer's type include___(what class)
cholinesterase inhibitors and N-Methyl-D-Aspartate (NMDA) Antagonist
How do Cholinesterase inhibitors act on the body of AD clients?

These drugs increase acetylcholine by inhibiting acetycholinesterase, the enzyme that degrades it.
How do N-Methyl-D-Aspartate (NMDA) Antagonist act on the body of an AD client?

By blocking NMDA receptors, the drug protects neurons from excessive stimulation by glutamate, an excitatory neurotransmitter responsible for neuronal death.
What other class of drugs can be given to AD clients who are experiencing agitation or depression?

antidepressants or tranquilizers
What is the major focus of nursing management for an AD client?

To help the client and caregiver maintain the highest possible quality of life by supporting mental and physical functions and ensuring safety.

Gerontologic consideration




Because cognitive changes alter older adults' roles and relationships, impacting their self-worth and evoking fear of the progression of the disease, What can help the client feel a sense of self-worth if the they have little or no family members or significant other?


photographs from younger years may help provide a sense of self

Because of mental decline, an elderly client with AD may not be able to verbally express pain. How should the nurse assess for pain?

Careful observation of facial expressions, body positioning, and by collaborating with caregivers and significant others
When caring for an AD client that wonders, what is an important caregiver teaching?

keep a means of identification on the client's person at all times

What would be a good teaching to help the caregivers of dementia clients?
Become involved with the local community mental health association; Join and attend meetings of a support group for caretakers of those who are cognitively impaired; investigate the services of a day care facility for occasional respite care.
__is a thought disorder characterized by deterioration in mental functioning, disturbances in sensory perception, and changes in affect (emotion).
Schizophrenia
Many neurotransmitter imbalances are involved in schizophrenia, but __ is believed to be the major cause of the symptoms.
dopamine excess

T or F




Schizophrenia is known to have a familial or genetic component.


True

Other theories on the Etiology of schizophrenia (besides genetics) believe it may result from ___ during pregnancy.

a viral infection experienced by the infected individual's mother
disturbed thinking

delusions

sensory experiences only the client perceives

hallucinations

belief in one's importance

grandiosity


Schizophrenia




symptoms usually begin during ___


late adolescence to early adulthood
The Schizophrenic client will manifest a variety of symptoms that are categorized as positive or negative. What is the difference?


-Positive symptoms include delusions, hallucinations, and fluent but disorganized speech.




-negative symptoms(defect symptoms) are marked by impoverished speech and an inability to enjoy relationships or express emotions.

Schizophrenia




Which is symptoms are more easily controlled by drugs positive or negative?


Positive
How is schizophrenia diagnosed?

Diagnosis is made primarily on the symptomatology and by ruling out other possible causes. CT and PET scans, MRIs, and brain mapping may show decreased brain size and activity, esp in the frontal and temporal lobe.